NQO1 Monoclonal Antibody | anti-NQO1 antibody
Anti - NQO1 (NAD(P)H Dehydrogenase Quinone 1, Azoreductase, Cytochrome b-5 Reductase, DHQU, Diaphorase (NADH/NADPH) (Cytochrome b-5 Reductase), Diaphorase 4, DIA4, Dioxin Inducible 1, DT Diaphorase, DTD, Menadione Reductase, NAD(P)H Menadione Oxidoreducta
Reactivity
Canine, Human, Monkey, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence
Purity
Purified
Synonyms
NQO1; Monoclonal Antibody; Anti - NQO1 (NAD(P)H Dehydrogenase Quinone 1; Azoreductase; Cytochrome b-5 Reductase; DHQU; Diaphorase (NADH/NADPH) (Cytochrome b-5 Reductase); Diaphorase 4; DIA4; Dioxin Inducible 1; DT Diaphorase; DTD; Menadione Reductase; NAD(P)H Menadione Oxidoreducta; NQO1 (NAD(P)H Dehydrogenase Quinone 1; NAD(P)H Menadione Oxidoreductase 1 Di; anti-NQO1 antibody
Host
Host: Mouse
Source: Human
Source: Human
Reactivity
Canine, Human, Monkey, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
9A53
Specificity
Specific for NQO1. It does not crossreact with NQO2. Species Crossreactivity: human and rat. Crossreacts with monkey and canine in immunohistochemistry. Cross-reactivity with mouse is extremely poor.
Purity/Purification
Purified
Form/Format
Purified
Tris-glycine and 150mM sodium chloride.
Tris-glycine and 150mM sodium chloride.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-NQO1 antibody
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence
Application Notes
Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry (paraffin-embedded sections). Other applications not tested.
Immunogen
Full length recombinant NQO1 (from human lung).
Cellular Localization
Cytoplasmic (primarily), nuclear (faintly)
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-NQO1 antibody
NQO1 is a 2-electron reductase that detoxifies quinones derived from the oxidation of phenolic metabolites of benzene. Individuals homozygous for the T/T form of the 609C-T polymorphism have an increased risk of benzene hematotoxicity.
Product Categories/Family for anti-NQO1 antibody
References
• 1. Siegel, et al. Clinical Can. Res. 4:2065-2070 (1998)2. Siegel, et al. Free Radical Biol. Med. 29:246-253 (2000)3. Slitt, A. L., Cherrington, N. J., Dieter, M. Z., Aleksunes, L. M., Scheffer, G. L., Huang, W., Moore, D. D., and Klaassen, C. D. (2006) trans-Stilbene Oxide Induces Expression of Genes Involved in Metabolism and Transport in Mouse Liver via CAR and Nrf2 Transcription Factors, 69, 1554-1563.
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Product Notes
The NQO1 (Catalog #AAA600793) is an Antibody produced from Host: Mouse Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti - NQO1 (NAD(P)H Dehydrogenase Quinone 1, Azoreductase, Cytochrome b-5 Reductase, DHQU, Diaphorase (NADH/NADPH) (Cytochrome b-5 Reductase), Diaphorase 4, DIA4, Dioxin Inducible 1, DT Diaphorase, DTD, Menadione Reductase, NAD(P)H Menadione Oxidoreducta reacts with Canine, Human, Monkey, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NQO1 can be used in a range of immunoassay formats including, but not limited to, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence. Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Researchers should empirically determine the suitability of the NQO1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NQO1, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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