Western Blot (WB)
(Western Blot analysis of AGGF1 expression in transfected 293T cell line by AGGF1 polyclonal antibody. Lane 1: AGGF1 transfected lysate (80.9kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human AGGF1 Polyclonal Antibody | anti-AGGF1 antibody
AGGF1 (GPATC7, GPATCH7, VG5Q, Angiogenic Factor with G Patch and FHA Domains 1, Angiogenic Factor VG5Q, G Patch Domain-containing Protein 7, Vasculogenesis Gene on 5q Protein, FLJ10283, HSU84971, HUS84971)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of AGGF1 expression in transfected 293T cell line by AGGF1 polyclonal antibody. Lane 1: AGGF1 transfected lysate (80.9kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of AGGF1 expression in transfected 293T cell line by AGGF1 polyclonal antibody. Lane 1: AGGF1 transfected lysate (80.9kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]
Uniprot Description
AGGF1: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS). KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Cell adhesion; RNA processing
Chromosomal Location of Human Ortholog: 5q13.3
Cellular Component: perinuclear region of cytoplasm; cytoplasm; extracellular region
Molecular Function: protein binding; nucleic acid binding
Biological Process: RNA processing; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; angiogenesis; cell adhesion; vasculogenesis
Disease: Klippel-trenaunay-weber Syndrome
Research Articles on AGGF1
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Product Notes
The AGGF1 aggf1 (Catalog #AAA6007674) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AGGF1 (GPATC7, GPATCH7, VG5Q, Angiogenic Factor with G Patch and FHA Domains 1, Angiogenic Factor VG5Q, G Patch Domain-containing Protein 7, Vasculogenesis Gene on 5q Protein, FLJ10283, HSU84971, HUS84971) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's AGGF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the AGGF1 aggf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MASEAPSPPR SPPPPTSPEP ELAQLRRKVE KLERELRSCK RQVREIEKLL HHTERLYQNA ESNNQELRTQ VEELSKILQR GRNEDNKKSD VEVQTENHAP WSISDYFYQT YYNDVSLPNK VTELSDQQDQ AIETSILNSK DHLQVENDAY PGTDRTENVK YRQVDHFASN SQEPASALAT EDTSLEGSSL AESLRAAAEA AVSQTGFSYD ENTGLYFDHS TGFYYDSENQ LYYDPSTGIY YYCDVESGRY QFHSRVDLQP YPTSSTKQSK DKKLKKKRKD PDSSATNEEK DLNSEDQKAF SVEHTSCNEE ENFANMKKKA KIGIHHKNSP PKVTVPTSGN TIESPLHENI SNSTSFKDEK IMETDSEPEE GEITDSQTED SYDEAITSEG NVTAEDSEDE DEDKIWPPCI RVIVIRSPVL QIGSLFIITA VNPATIGREK DMEHTLRIPE VGVSKFHAEI YFDHDLQSYV LVDQGSQNGT IVNGKQILQP KTKCDPYVLE HGDEVKIGET VLSFHIHPGS DTCDGCERGQ VRAHLRLDKK DESFVGPTLS KEEKELEGRK ELKKIRVKYG LQNTEYEDEK TLKNPKYKDR AGKRREQVGS EGTFQRDDAP ASVHSEITDS NKGRKLLEKM GWKKGEGLGK DGGGMKTPIQ LQLRRTHAGL GTGKPSSFED VHLLQNKNKK NWDKARERFT ENFPETKPQK DDPGTMPWVK GTLE. It is sometimes possible for the material contained within the vial of "AGGF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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