Western Blot (WB)
(Western Blot analysis of FMO2 expression in transfected 293T cell line by FMO2 polyclonal antibody. Lane 1: FMO2 transfected lysate (53.6kD). Lane 2: Non-transfected lysate.)
Rabbit anti-Human FMO2 Polyclonal Antibody | anti-FMO2 antibody
FMO2 (Dimethylaniline Monooxygenase [N-oxide-forming] 2, Pulmonary Flavin-containing Monooxygenase 2, FMO 2, FMO 1B1, Dimethylaniline Oxidase 2)
Purified by Protein A affinity chromatography.
Purified by Protein A affinity chromatography.
Western Blot (WB)
(Western Blot analysis of FMO2 expression in transfected 293T cell line by FMO2 polyclonal antibody. Lane 1: FMO2 transfected lysate (53.6kD). Lane 2: Non-transfected lysate.)
Western Blot (WB)
(Western Blot analysis of FMO2 expression in transfected 293T cell line by FMO2 polyclonal antibody. Lane 1: FMO2 transfected lysate (53.6kD). Lane 2: Non-transfected lysate.)
NCBI and Uniprot Product Information
NCBI Description
The flavin-containing monooxygenases are NADPH-dependent enzymes that catalyze the oxidation of many drugs and xenobiotics. In most mammals, there is a flavin-containing monooxygenase that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, in some human populations, this enzyme is truncated and likely degraded rapidly. The protein encoded by this gene represents the truncated form and apparently has no catalytic activity. A functional allele found in African Americans has been reported, but no sequence evidence has been deposited to support the finding. This gene is found in a cluster with the FMO1, FMO3, and FMO4 genes on chromosome 1. [provided by RefSeq, Jun 2013]
Uniprot Description
FMO2: Catalyzes the N-oxidation of certain primary alkylamines to their oximes via an N-hydroxylamine intermediate. Inactive toward certain tertiary amines, such as imipramine or chloropromazine. Can catalyze the S-oxidation of methimazole. The truncated form is catalytically inactive. Belongs to the FMO family.
Protein type: Xenobiotic Metabolism - drug metabolism - cytochrome P450; Oxidoreductase; EC 1.14.13.8
Chromosomal Location of Human Ortholog: 1q24.3
Cellular Component: endoplasmic reticulum membrane; membrane; integral to membrane
Molecular Function: FAD binding; NADP binding; monooxygenase activity; flavin-containing monooxygenase activity
Biological Process: organic acid metabolic process; xenobiotic metabolic process; toxin metabolic process; drug metabolic process; NADP metabolic process
Research Articles on FMO2
Similar Products
Product Notes
The FMO2 fmo2 (Catalog #AAA6007539) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The FMO2 (Dimethylaniline Monooxygenase [N-oxide-forming] 2, Pulmonary Flavin-containing Monooxygenase 2, FMO 2, FMO 1B1, Dimethylaniline Oxidase 2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FMO2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Researchers should empirically determine the suitability of the FMO2 fmo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MAKKVAVIGA GVSGLISLKC CVDEGLEPTC FERTEDIGGV WRFKENVEDG RASIYQSVVT NTSKEMSCFS DFPMPEDFPN FLHNSKLLEY FRIFAKKFDL LKYIQFQTTV LSVRKCPDFS SSGQWKVVTQ SNGKEQSAVF DAVMVCSGHH ILPHIPLKSF PGMERFKGQY FHSRQYKHPD GFEGKRILVI GMGNSGSDIA VELSKNAAQV FISTRHGTWV MSRISEDGYP WDSVFHTRFR SMLRNVLPRT AVKWMIEQQM NRWFNHENYG LEPQNKYIMK EPVLNDDVPS RLLCGAIKVK STVKELTETS AIFEDGTVEE NIDVIIFATG YSFSFPFLED SLVKVENNMV SLYKYIFPAH LDKSTLACIG LIQPLGSIFP TAELQARWVT RVFKGLCSLP SERTMMMDII KRNEKRIDLF GESQSQTLQT NYVDYLDELA LEIGAKPDFC SLLFKDPKLA VRLYFGPCNS Y. It is sometimes possible for the material contained within the vial of "FMO2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
