Mouse anti-Human MTMR8 Polyclonal Antibody | anti-MTMR9 antibody

MTMR8 (Myotubularin-related Protein 8, FLJ20126)

Cat. Num. AAA6002246

• Gene Names: MTMR9; MTMR8; C8orf9; LIP-STYX
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: MTMR8; Polyclonal Antibody; MTMR8 (Myotubularin-related Protein 8; FLJ20126); Anti -MTMR8 (Myotubularin-related Protein 8; anti-MTMR9 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human MTMR8.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MDHITVPKVENVKLVDRYVSKKPANGILYLTATHLIYVEASGAARKETWIALHHIATVEKLPITSLGCPLTLRCKNFRVAHFVLDSDLVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRESGWKLIDPISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPIFTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNPSTVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPEEICTCSQLGNILSQHLGSPLTNPLGFMGINGDLNTLMENGTLSREGGLRAQMDQVKSQGADLHHNCCEIVGSLRAINISGDVGISEAMGISGDMCTFEATGFSKDLGICGAMDISEATGISGNLGISEARGFSGDMGILGDTGISKASTKEADYSKHQ

• Applicable Applications for anti-MTMR9 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence and Western Blot.; Dilution: Immunofluorescence: 10ug/ml
• Immunogen: Full length human MTMR8, aa1-704 (NP_060147.2).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of MTMR8 expression in transfected 293T cell line by MTMR8 polyclonal antibody. Lane 1: MTMR8 transfected lysate (77.44kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of purified antibody to MTMR8 on HepG2 cell. [antibody concentration 10ug/ml].)

Related Product Information for anti-MTMR9 antibody

MTMR8 is a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate.

Product Categories/Family for anti-MTMR9 antibody

Antibodies; Abs to Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 19923424
• NCBI GeneID: 66036
• NCBI Accession #: NP_056273.2
• NCBI GenBank Nucleotide #: NM_015458.3
• UniProt Accession #: Q96QG7; Q52LU3; Q8WW11; Q96QG6; Q9NX50
• Molecular Weight: 63,462 Da
• NCBI Official Full Name: myotubularin-related protein 9
• NCBI Official Synonym Full Names: myotubularin related protein 9
• NCBI Official Symbol: MTMR9
• NCBI Official Synonym Symbols: MTMR8; C8orf9; LIP-STYX
• NCBI Protein Information: myotubularin-related protein 9; myotubularin related protein 8
• UniProt Protein Name: Myotubularin-related protein 9
• UniProt Gene Name: MTMR9
• UniProt Synonym Gene Names: C8orf9; MTMR8
• UniProt Entry Name: MTMR9_HUMAN

NCBI Description

This gene encodes a myotubularin-related protein that is atypical to most other members of the myotubularin-related protein family because it has no dual-specificity phosphatase domain. The encoded protein contains a double-helical motif similar to the SET interaction domain, which is thought to have a role in the control of cell proliferation. In mouse, a protein similar to the encoded protein binds with MTMR7, and together they dephosphorylate phosphatidylinositol 3-phosphate and inositol 1,3-bisphosphate. [provided by RefSeq, Jul 2008]

Uniprot Description

MTMR9: Probable pseudophosphatase. Contains a Gly residue instead of a conserved Cys residue in the dsPTPase catalytic loop which renders it catalytically inactive as a phosphatase (Potential). Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

Protein type: Protein phosphatase, tyrosine (non-receptor); Protein phosphatase, regulatory subunit

Chromosomal Location of Human Ortholog: 8p23-p22

Cellular Component: cytoplasm

Molecular Function: protein binding; phosphoric monoester hydrolase activity; enzyme regulator activity

Biological Process: dephosphorylation; regulation of catalytic activity