Mouse anti-Human SYTL3 Polyclonal Antibody | anti-SYTL3 antibody

SYTL3 (Synaptotagmin-like Protein 3, SLP3, Exophilin-6)

Cat. Num. AAA6000895

• Gene Names: SYTL3; SLP3
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: SYTL3; Polyclonal Antibody; SYTL3 (Synaptotagmin-like Protein 3; SLP3; Exophilin-6); Anti -SYTL3 (Synaptotagmin-like Protein 3; anti-SYTL3 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SYTL3.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKEKCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWFYEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRLQEFGQFRGFNKSVENLFLSLATHVKKLSKSQNDMTSEKHLLATGPRQCVGQTERRSQSDTAVNVTTRKVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGNFDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGKRKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDFEDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHGQLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGVTPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSQSKLQWQKVLSSPNLWTDMTLVLH

• Applicable Applications for anti-SYTL3 antibody: Western Blot (WB)
• Application Notes: Suitable for use in Western Blot.
• Immunogen: Full length human SYTL3, aa1-610.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of SYTL3 expression in transfected 293T cell line by SYTL3 polyclonal antibody. Lane 1: SYTL3 transfected lysate (67.1kD). Lane 2: Non-transfected lysate.)

Product Categories/Family for anti-SYTL3 antibody

Antibodies; Abs to Syntaxin; Synaptotagmin; Synaptophysin

NCBI and Uniprot Product Information

• NCBI GI #: 71680913
• NCBI GeneID: 94120
• UniProt Accession #: Q4VX76; Q496J4; Q496J6; Q5U3B9
• Molecular Weight: 68,560 Da
• NCBI Official Full Name: SYTL3 protein
• NCBI Official Synonym Full Names: synaptotagmin-like 3
• NCBI Official Symbol: SYTL3
• NCBI Official Synonym Symbols: SLP3
• NCBI Protein Information: synaptotagmin-like protein 3; exophilin-6
• UniProt Protein Name: Synaptotagmin-like protein 3
• Protein Family: Synaptotagmin-like protein
• UniProt Gene Name: SYTL3
• UniProt Synonym Gene Names: SLP3
• UniProt Entry Name: SYTL3_HUMAN

NCBI Description

The protein encoded by this gene belongs to the family of synaptotagmin-like proteins (SLPs). SLPs are peripheral membrane proteins that interact with RAB27A protein, and play a role in vesicular trafficking. Unlike, SLPs 1 and 2, this protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

Uniprot Description

SYTL3: May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q25.3

Cellular Component: extrinsic to plasma membrane; endomembrane system

Molecular Function: calcium-dependent phospholipid binding; neurexin binding; Rab GTPase binding

Biological Process: intracellular protein transport; exocytosis