Mouse anti-Human FPRL1 2nd extracellular loop Monoclonal Antibody
mAb anti-Human FPRL1 2nd extracellular loop
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Protein G affinity purified
Synonyms
FPRL1 2nd extracellular loop; Monoclonal Antibody; mAb anti-Human FPRL1 2nd extracellular loop; Formyl Peptide Receptor-like 1 C-terminal (FPRL-1) 2nd extracellular loop; Mouse monoclonal antibody against the 2nd extracellular loop of human formyl peptide-receptor-like-1 (FPRL1); anti-FPRL1 2nd extracellular loop antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
B7H10
Specificity
This antibody is reactive to the peptide (ASWGGTPEERLKC) from the 2nd extracellular loop of human FPRL1 and is also reactive to intact human FPRL1.
Formyl Peptide Receptor-like 1 C-terminal (FPRL-1) 2nd extracellular loop
Formyl Peptide Receptor-like 1 C-terminal (FPRL-1) 2nd extracellular loop
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized from a solution in 0.01M PBS pH7.2
Applicable Applications for anti-FPRL1 2nd extracellular loop antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: In indirect ELISA, the antibody is reactive to the peptide (ASWGGTPEERLKC) from the 2nd extracellular loop of human FPRL1.
Target Protein
The 2nd extracellular loop of human formyl peptide-receptor-like-1 (FPRL1)
Immunogen
A short peptide (ASWGGTPEERLKC) corresponding to the amino acids on the 2nd extracellular loop of human FPRL1 is conjugated with KLH for immunization.
Myeloma
Sp2/0-Ag14
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to adjust the final concentration to 1.00 mg/ml.
Research Area
G-protein coupled membrane receptor, chemotaxis and Alzheimer's disease.
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-FPRL1 2nd extracellular loop antibody
Description: Mouse monoclonal antibody against the 2nd extracellular loop of human formyl peptide-receptor-like-1 (FPRL1)
background: Human formyl peptide receptor-like 1(FPRL1) is a G-protein coupled seven transmembrane receptor. The receptor can bind to the formyl peptides derived from the degradation of the cell wall of infected bacteria and host cells. FPRL1 expressed on the cell surface of neutrophils and other leukocytes mediates the chemotaxis of these cells toward infected site. It has been reported that acute phase protein SAA is also a ligand of FPRL1 and SAA can induce the secretion of IL-8 and TNF-alpha by neutrophil through FPRL1 signalling. FPRL1 has also been shown to mediate the chemotaxis of microglia by Abeta42 peptide and the internalization of Abeta42 peptide into cytoplasma of macrophage, indicating that FRPL1 may participate in the Abeta42 peptide elicited pathogenesis in Alzheimer's disease.
background: Human formyl peptide receptor-like 1(FPRL1) is a G-protein coupled seven transmembrane receptor. The receptor can bind to the formyl peptides derived from the degradation of the cell wall of infected bacteria and host cells. FPRL1 expressed on the cell surface of neutrophils and other leukocytes mediates the chemotaxis of these cells toward infected site. It has been reported that acute phase protein SAA is also a ligand of FPRL1 and SAA can induce the secretion of IL-8 and TNF-alpha by neutrophil through FPRL1 signalling. FPRL1 has also been shown to mediate the chemotaxis of microglia by Abeta42 peptide and the internalization of Abeta42 peptide into cytoplasma of macrophage, indicating that FRPL1 may participate in the Abeta42 peptide elicited pathogenesis in Alzheimer's disease.
Product Categories/Family for anti-FPRL1 2nd extracellular loop antibody
Similar Products
Product Notes
The FPRL1 2nd extracellular loop (Catalog #AAA592376) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human FPRL1 2nd extracellular loop reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's FPRL1 2nd extracellular loop can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: In indirect ELISA, the antibody is reactive to the peptide (ASWGGTPEERLKC) from the 2nd extracellular loop of human FPRL1. Researchers should empirically determine the suitability of the FPRL1 2nd extracellular loop for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "FPRL1 2nd extracellular loop, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
