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Mouse Colorectal Carcinoma/CD3 Monoclonal Antibody

mAb anti-Human Colorectal Carcinoma/CD3

Reactivity
Human. Others not tested
Applications
ELISA, Flow Cytometry, Functional Assay
Purity
Protein G affinity purified
Synonyms
Colorectal Carcinoma/CD3; Monoclonal Antibody; mAb anti-Human Colorectal Carcinoma/CD3; Colorectal Carcinoma/CD3 (Bi-specific); anti-Colorectal Carcinoma/CD3 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human. Others not tested
Clonality
Monoclonal
Isotype
IgG1/ IgG2a
Clone Number
BS-1
Specificity
This antibody recognizes human colorectal carcinoma related protein and CD3 molecule on T cells.
Colorectal Carcinoma/CD3 (Bi-specific)
Purity/Purification
Protein G affinity purified
Form/Format
Lyophilized in 0.01M PBS, pH 7.0
Applicable Applications for anti-Colorectal Carcinoma/CD3 antibody
ELISA (EIA), Flow Cytometry (FC/FACS)
Application Notes
ELISA: The bi-specific antibody has been shown to detect the presence of the tumor-associated antigen in the serum of patients with colorectal carcinoma, and reacted with mucin-like oncofetal pancarcinoma antigen, glycoprotein TAG-72.
Target Protein
Human colorectal carcinoma related protein and cluster of differentiation 3 (CD3) on T-cells.
Immunogen
The original CRC mAb (Y94) used human colorectal carcinoma as immunogen. The original CD3 mAb (JXT3) used human peripheral T lymphocytes as immunogen
Myeloma
No information
Light Chain
Kappa
Reconstitution
Double distilled water is recommended to reconstitute the antibody
Research Area
Immunology, T-cell receptor. Oncology
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-Colorectal Carcinoma/CD3 antibody
The human colorectal carcinoma antigen (CRC) monoclonal antibody-secreted hybridoma cell line was transfected by mpSV2gpt. The human CD3 monoclonal antibody-secreted hybridoma cell line (JXT3) was transfected by mpSV2neo. The production of quadroma CRCgpt/CD3neo included a conventional somatic fusion between CRC and JXT3 cells and were selected and cloned in the media containing both mycophenolic acid and geneticin. Quadromas showing both murine IgG1 and IgG2a were selected and subcloned for the purification of hybrid bispecific antibody CRC/CD3. This product is Protein G affinity purified.
Product Categories/Family for anti-Colorectal Carcinoma/CD3 antibody

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Product Notes

The Colorectal Carcinoma/CD3 (Catalog #AAA592236) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The mAb anti-Human Colorectal Carcinoma/CD3 reacts with Human. Others not tested and may cross-react with other species as described in the data sheet. AAA Biotech's Colorectal Carcinoma/CD3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Flow Cytometry (FC/FACS). ELISA: The bi-specific antibody has been shown to detect the presence of the tumor-associated antigen in the serum of patients with colorectal carcinoma, and reacted with mucin-like oncofetal pancarcinoma antigen, glycoprotein TAG-72. Researchers should empirically determine the suitability of the Colorectal Carcinoma/CD3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Colorectal Carcinoma/CD3, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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