Testing Data
Mouse TC-PTP Monoclonal Antibody | anti-TC-PTP antibody
TC-PTP (N term) Mouse Monoclonal Antibody (3E2) - Purified
Applications
Western Blot
Purity
Purified
Synonyms
TC-PTP; Monoclonal Antibody; TC-PTP (N term) Mouse Monoclonal Antibody (3E2) - Purified; Anti-TC-PTP Antibody (3E2) Purified; Purified T cell protein tyrosine phosphatase (TC-PTP) Mouse Monoclonal Antibody; anti-T cell protein tyrosine phosphatase; anti-tc-ptp; anti-TC-PTP antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3E2
Specificity
Human, Monkey, Rat, Mouse
Purity/Purification
Purified
Applicable Applications for anti-TC-PTP antibody
Western Blot (WB)
Conjugation
None
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for anti-TC-PTP antibody
Protein tyrosine phosphatases (PTP) belong to a large family of enzymes involved in the regulation of cellular signaling and homeostasis. They all possess a 240 amino acid PTP domain. The T-cell protein tyrosine phosphatase (TC-PTP) is predominantly expressed in the hematopoietic lineage. TC-PTP null mice suffer severe defects in the hematopoietic compartment and die at 3-5 weeks of age from severe anemia. TC-PTP -/- murine embryonic fibroblasts have a slow progression through the G1 phase of the cell cycle and have compromised NF- B activation. JAK 1 and 3 have been identified as physiological substrates of TC-PTP. Recent genetic studies have revealed an association between the PTPN2 (TC-PTP) gene and diseases like type 1 diabetes and Crohn’s disease.
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Product Notes
The TC-PTP (Catalog #AAA588302) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's TC-PTP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TC-PTP for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TC-PTP, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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