survivin (baculoviral IAP repeat-containing protein 5), Inhibitor
survivin (baculoviral IAP repeat-containing protein 5) (21-28)
Purity
98.00%
Synonyms
survivin (baculoviral IAP repeat-containing protein 5); survivin (baculoviral IAP repeat-containing protein 5) (21-28); inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: >=105.2mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C54H73N11O11
SMILES
NC(C(C)O)C(NC(CC1=CC=CC=C1)C(NC(CCCCN)C(NC(CC(N)=O)C(NC(CC2=CNC3=C2C=CC=C3)C(N4C(C(NC(CC5=CC=CC=C5)C(NC(CC(C)C)C(O)=O)=O)=O)CCC4)=O)=O)=O)=O)=O
In Vitro
Survivin relates to poor disease outcome in a variety of tumors, i.e., neuroblastoma3, colorectal cancer4, non-small-cell lung cancers5, B-cell lymphoma6, T-cell leukemia7, hepatocellular carcinoma, esophageal carcinoma, rectal cancer, glioma, bladder cancer, soft tissue sarcoma, and astrocytic tumors. Survivin mRNA, as measured by quantitative RT-PCR in the primary tumor, has strong and independent prognostic value in human breast cancer. Survivin mRNA concentrations in the tumor can be used to classify breast cancer patients into different risk groups. 8 Cells that are unresponsive to apoptotic triggers will also be more resistant to cytotoxic treatment, as are cells that overexpress survivin9.
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
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Product Notes
The survivin (baculoviral IAP repeat-containing protein 5) (Catalog #AAA5764247) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "survivin (baculoviral IAP repeat-containing protein 5), Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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