Methyl rosmarinate, Inhibitor
Methyl rosmarinate
Purity
98.00%
Synonyms
Methyl rosmarinate; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C19H18O8
SMILES
COC([C@@H](Cc(cc1)cc(O)c1O)OC(/C=C/c(cc1)cc(O)c1O)=O)=O
CAS Number
99353-00-1
Target & IC50
Tyrosinase
Antifection
MMP
Antifection
MMP
In Vitro
An initial microtiter dilution assay indicated activity of compounds against S. carnosus LTH1502, whereas esters with chain lengths, RA, n-Methyl rosmarinate (RE1), n-dodecyl rosmarinate (RE12), and n-octadecyl rosmarinate (RE18) were used in a time-kill assay S. carnosus LTH1502. Compounds were added at 0.75mM in the log phase, 5mM in the exponential phase, 10mM in the stationary phase. RA had no effect in the lag and exponential phase but decreased cell counts during the stationary phase. In contrast, RE1 and RE12 decreased cell number in all three phase, will RE12 reducing counts most rapidly. Addition of RE18 did not affect regardless of the growth phase[1]
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Methyl rosmarinate, inhibitor
Methyl rosmarinate is a noncompetitive tyrosinase inhibitor which is isolated from Rabdosia serra, with an IC50 of 0.28mM for mushroom tyrosinase.Methyl rosmarinate shows antioxidative, and antifungal activities. It has inhibitory activities against tyrosinase, alpha+/--glucosidase, and matrix metalloproteinase-1 (MMP-1).
Product Categories/Family for Methyl rosmarinate, inhibitor
References
Impact of fatty acid chain length of rosmarinate esters on their antimicrobial activity against Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263.J Food Prot. 2013 Sep;76(9):1539-48.
Impact of fatty acid chain length of rosmarinate esters on their antimicrobial activity against Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263.J Food Prot. 2013 Sep;76(9):1539-48.
[Chemical constituents of Hyptis rhomboidea and their antifungal activity].Zhongguo Zhong Yao Za Zhi. 2014 Jun;39(12):2284-8.
Impact of fatty acid chain length of rosmarinate esters on their antimicrobial activity against Staphylococcus carnosus LTH1502 and Escherichia coli K-12 LTH4263.J Food Prot. 2013 Sep;76(9):1539-48.
[Chemical constituents of Hyptis rhomboidea and their antifungal activity].Zhongguo Zhong Yao Za Zhi. 2014 Jun;39(12):2284-8.
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Product Notes
The Methyl rosmarinate (Catalog #AAA5760647) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Methyl rosmarinate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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