Structure
BAY-545, inhibitor
BAY-545
Purity
98.00%
Synonyms
BAY-545; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
DMSO: 145mg/mL (334.53mM)
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C18H22F3N3O4S
SMILES
CCn1c(=O)n(CCC(F)(F)F)c2sc(C(=O)N3CCC(O)CC3)c(C)c2c1=O
CAS Number
1699717-32-2
Target & IC50
A2B adenosine receptor: ic50 59nM
A2B adenosine receptor: ic50 59nM
Human A2B adenosine receptor: ic50 66nM
Mouse A2B adenosine receptor: ic50 400nM
Rat A2B adenosine receptor: ic50 280nM
Human A1 adenosine receptor: ic50 1300nM
Human A2A adenosine receptor: ic50 820nM
Mouse A2A adenosine receptor: ic50 470nM
Rat A2A adenosine receptor: ic50 750nM
A2B adenosine receptor: ic50 59nM
Human A2B adenosine receptor: ic50 66nM
Mouse A2B adenosine receptor: ic50 400nM
Rat A2B adenosine receptor: ic50 280nM
Human A1 adenosine receptor: ic50 1300nM
Human A2A adenosine receptor: ic50 820nM
Mouse A2A adenosine receptor: ic50 470nM
Rat A2A adenosine receptor: ic50 750nM
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Structure
Related Product Information for BAY-545, inhibitor
BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59nM).
Product Categories/Family for BAY-545, inhibitor
References
Harter M, et al. Novel non-xanthine antagonist of the A2B adenosine receptor: From HTS hit to lead structure. Eur J Med Chem.
Similar Products
Product Notes
The BAY-545 (Catalog #AAA5759304) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "BAY-545, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
