IL-11 receptor alpha Active Protein | IL11RA active protein
Mouse IL-11 receptor alpha Recombinant
Endotoxin level was found to be less than 0.1 ng/ug (1EU/ug).
• recombinant soluble interleukin-11 (il-11) receptor -chain can act as an il-11 antagonist .Blood, Dec 1997; 90: 4403 - 4412.
NCBI and Uniprot Product Information
Uniprot Description
IL11RA: Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number. Defects in IL11RA are a cause of craniosynostosis and dental anomalies (CRSDA). CRSDA is a disorder characterized by craniosynostosis, maxillary hypoplasia, and dental anomalies, including malocclusion, delayed and ectopic tooth eruption, and/or supernumerary teeth. Some patients also display minor digit anomalies, such as syndactyly and/or clinodactyly. Belongs to the type I cytokine receptor family. Type 3 subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: membrane; integral to membrane
Molecular Function: interleukin-11 binding; hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-11 receptor activity
Biological Process: maternal process involved in pregnancy; natural killer cell differentiation; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; decidualization; placenta development
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Product Notes
The IL11RA il11ra1 (Catalog #AAA553276) is an Active Protein produced from HEK Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IL-11 receptor alpha, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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