Granzyme B Active Protein | CXCL10 active protein
Granzyme B protein
Applications
User optimized
Purity
> 98% pure
Synonyms
Granzyme B; Granzyme B protein; CXCL10 active protein
Host
Mouse
Purity/Purification
> 98% pure
Form/Format
Supplied as a lyophilized powder.
Sequence
Region of Granzyme B protein corresponding to amino acids IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS.
Sequence Length
102
Applicable Applications for CXCL10 active protein
User optimized
Protein Type
Recombinant
Biological Significance
Granzyme B is a cysteine protease found in the cytoplasmic granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme B is required for the induction of target cell lysis, which occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms. Proteolytic cleavage of substrates by Granzyme B takes place primarily after aspartic acid residues. Recombinant Mouse
Bioactivity
Determined by its ability to cleave a synthetic chromogentic Granzyme B substrate. The expected specific activity, when using the Ac-IEPD-pNA substrate at 250C, is greater than 750 nM/min per ug of enzyme.
Endotoxin Levels
Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Expression System
Baculovirus
Preparation and Storage
Store at 4 degree C until reconstitution. Following reconstitution aliquot and freeze at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for CXCL10 active protein
Purified recombinant Mouse Granzyme B protein
Product Categories/Family for CXCL10 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
28.9 kDa
NCBI Official Full Name
gamma interferon inducible protein 10
NCBI Official Symbol
CXCL10
NCBI Protein Information
C-X-C motif chemokine 10
UniProt Protein Name
C-X-C motif chemokine 10
Protein Family
UniProt Gene Name
CXCL10
UniProt Entry Name
CXL10_BOVIN
Uniprot Description
Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3 ().
Research Articles on CXCL10
1. IL-17A was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.
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Product Notes
The CXCL10 cxcl10 (Catalog #AAA539538) is an Active Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Granzyme B can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the CXCL10 cxcl10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of Granzyme B protein correspond ing to amino acids IIGGHEVKPH SRPYMALLSI KDQQPEAICG GFLIREDFVL TAAHCEGSII NVTLGAHNIK EQEKTQQVIP MVKCIPHPDY NPKTFSNDIM LLKLKSKAKR TRAVRPLNLP RRNVNVKPGD VCYVAGWGRM APMGKYSNTL QEVELTVQKD RECESYFKNR YNKTNQICAG DPKTKRASFR GDSGGPLVCK KVAAGIVSYG YKDGSPPRAF TKVSSFLSWI KKTMKSS. It is sometimes possible for the material contained within the vial of "Granzyme B, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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