MCP1 active protein
MCP1 protein
Purity
>98% by SDS-PAGE gel and HPLC analysis
Synonyms
MCP1; MCP1 protein; MCP-1 protein; MCAF protein; MCP 1 protein; MCP 1; MCP-1; CCL2 protein; JE protein; Monocyte Chemotactic Protein-1 protein; Mouse protein; MCP1 active protein
Host
E. Coli
Purity/Purification
>98% by SDS-PAGE gel and HPLC analysis
Form/Format
Lyophilized with no additives. Reconstitute in water to 0.1-1.0mg/ml. After intial reconstitution, futher dilute in a buffer containing a carrier protein or stabilizer.
Concentration
10ug, lyophilized (varies by lot)
Grade
Recombinant
Endotoxin
<0.1ng/ug of protein (<1EU/ug)
Species
Human
Residues
Region of MCP1 protein corresponding to amino acids QPDAVNAPLT CCYSFTGKMI PMSRLENYKR ITSSRCPKEA VVFVTKLKRE ICADPNKEWV QKYIRKLDQN QVRSETTVFY KIASTLRTSA PLNVNLTHKS EANASTLFST TTSSTSVEVT SMTEN.
Biohazard
Use standard laboratory precautions when handling this material.
Bioactivity
Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml.
Biological Significance
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species.
Preparation and Storage
Ships on blue ice. Upon receipt store at 4°C short term, -20°C long term. Avoid repeat freeze-thaws.
Related Product Information for MCP1 active protein
Purified recombinant Human MCP1 protein
Product Categories/Family for MCP1 active protein
References
Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons; Elisabeth Fr¸ylanda, Elena Didenko Pedersenb, Anne-Katrine Kvisselc, Runar Almaasd, Anne Pharob, Bj¸rn Steen Sk¥lhegge, Tom Eirik Mollnesb, Terje Rootwelt (Brain Research: Volume: 1113 Issue: 1 Page: 64-73 DOI: 10.1016/j.brainres.2006.07.051)
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
14.0 kDa
NCBI Official Full Name
monocyte chemotactic protein 1, partial
UniProt Protein Name
Monocyte chemotactic protein 1
Protein Family
UniProt Gene Name
MCP1
UniProt Entry Name
Q9BG83_PONPY
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Product Notes
The MCP1 mcp1 (Catalog #AAA538145) is an Active Protein produced from E. Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MCP1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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