Myoglobin Native Protein | MB native protein

Myoglobin protein (cardiac)

Cat. Num. AAA537321

• Gene Names: MB; PVALB; myoglobgin
• Applications: User optimized
• Purity: > 95% (by SDS-PAGE)
• Synonyms: Myoglobin; Myoglobin protein (cardiac); Heart Myoglobin Protein; MB native protein

• Purity/Purification: > 95% (by SDS-PAGE)
• Form/Format: Supplied as a liquid in PBS, pH 7.5, with 0.09% NaN₃ as a preservative
• Concentration: 3.5mg/ml by Lowry (varies by lot)
• Sequence Length: 154

• Applicable Applications for MB native protein: User optimized
• Species: Human
• Source: Prepared from human heart tissue
• Protein Type: Native
• Biological Significance: Myoglobin is an iron- and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals. It is related to hemoglobin, which is the iron- and oxygen-binding protein in blood, specifically in the red blood cells. The only time myoglobin is found in the bloodstream is when it is released following muscle injury.
• Grade: Ultra Pure
• Contaminants: 4-12% Bis Tris NuPage gel, SDS-PAGE reduced shows one brand corresponding to the molecular weight of Myoglobin
• Biohazard: Non-reactive for HIV-1/HCV/HBV by NAT, HBsAg, HCV Ab, HIV 1&2 Ab, and RPR by currently approved FDA methods. Use appropriate laboratory precautions when handling this product.
• Preparation and Storage: Store at 4 degree C. DO NOT FREEZE.

Related Product Information for MB native protein

Purified native Human Myoglobin protein (cardiac)

Product Categories/Family for MB native protein

Cardiac Markers; Native Protein

NCBI and Uniprot Product Information

• NCBI GI #: 44955888
• NCBI GeneID: 4151
• NCBI Accession #: NP_976312.1
• NCBI GenBank Nucleotide #: NM_203378.1
• UniProt Accession #: P02144; Q52H51; Q5THY7
• Molecular Weight: 17,184 Da
• NCBI Official Full Name: myoglobin
• NCBI Official Synonym Full Names: myoglobin
• NCBI Official Symbol: MB
• NCBI Official Synonym Symbols: PVALB; myoglobgin
• NCBI Protein Information: myoglobin
• UniProt Protein Name: Myoglobin
• Protein Family: Myoglobin
• UniProt Gene Name: MB
• UniProt Entry Name: MYG_HUMAN

NCBI Description

This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

MB: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. Belongs to the globin family.

Protein type: Carrier

Chromosomal Location of Human Ortholog: 22q13.1

Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity

Biological Process: slow-twitch skeletal muscle fiber contraction; response to hydrogen peroxide; oxygen transport; heart development; brown fat cell differentiation; response to hormone stimulus; response to hypoxia; enucleate erythrocyte differentiation