Rabbit PDGF AA Polyclonal Antibody | anti-PDGF AA antibody
PDGF AA antibody
Gene Names
pdgfa; pdgf; pdgf-a
Reactivity
Human PDGF AA
Applications
ELISA, Western Blot
Synonyms
PDGF AA; Polyclonal Antibody; PDGF AA antibody; Polyclonal PDGF AA; Anti-PDGF AA; Platelet-Derived Growth Factor-AA; GDGF; Glioma-derived growth factor; ODGF; Osteosarcoma-derived Growth Factor; anti-PDGF AA antibody
Host
Rabbit
Reactivity
Human PDGF AA
Clonality
Polyclonal
Specificity
Human PDGF AA
Form/Format
Lyophilized from PBS, pH 7.4. Reconstitute in sterile water at a concentration of >0.2 mg/ml.
Sequence Length
226
Applicable Applications for anti-PDGF AA antibody
ELISA (EIA), Inhibition, Western Blot (WB)
Application Notes
ELISA: 0.5-2 ug/ml
Inhibition: 0.13-0.2 ug/ml
WB: 0.1-0.2 ug/ml
Inhibition: 0.13-0.2 ug/ml
WB: 0.1-0.2 ug/ml
Biological Significance
PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs; PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet a-granules and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development.
Immunogen
PDGF AA antibody was raised in rabbit using highly pure recombinant human PDGF-AA as the immunogen.
Preparation and Storage
Store at -20 degree C until reconstitution. Following reconstitution product may be stored at 4 degree C in the short term. For long term storage aliquot and freeze at -20 degree C. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-PDGF AA antibody
Affinity purified Rabbit polyclonal PDGF AA antibody
Product Categories/Family for anti-PDGF AA antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28.7 kDa (predicted detection band MW)
NCBI Official Full Name
platelet-derived growth factor subunit A
NCBI Official Synonym Full Names
platelet-derived growth factor alpha polypeptide
NCBI Official Symbol
pdgfa
NCBI Official Synonym Symbols
pdgf; pdgf-a
NCBI Protein Information
platelet-derived growth factor subunit A
UniProt Protein Name
Platelet-derived growth factor subunit A
UniProt Gene Name
pdgfa
UniProt Synonym Gene Names
PDGF subunit A
UniProt Entry Name
PDGFA_XENLA
Uniprot Description
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Signaling is modulated by the formation of heterodimers with PDGFB ().
Research Articles on PDGF AA
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Product Notes
The PDGF AA pdgfa (Catalog #AAA534710) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDGF AA antibody reacts with Human PDGF AA and may cross-react with other species as described in the data sheet. AAA Biotech's PDGF AA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). ELISA: 0.5-2 ug/ml Inhibition: 0.13-0.2 ug/ml WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the PDGF AA pdgfa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDGF AA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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