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Rabbit anti-Human GLUT2 Polyclonal Antibody | anti-GLUT2 antibody

GLUT2 antibody

Gene Names
Slc2a2; Glut2; Glut-2; AI266973
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
GLUT2; Polyclonal Antibody; GLUT2 antibody; Polyclonal GLUT2; Anti-GLUT2; Glucose Transporter 2; GLUT 2; GLUT-2; GLUT -2; anti-GLUT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Form/Format
Supplied in PBS with 0.05% NaN3.
Sequence Length
5
Applicable Applications for anti-GLUT2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
ELISA: 0.5-1 ug/ml
IHC: 2-10 ug/ml
WB: 1-10 ug/ml
Biological Significance
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Glut isoforms differ in their tissue expression, substrate specificity and kinetic characteristics. Glut-2 is present in liver, intestine, kidney and betapancreatic islet cells and likely mediates the bidirectional transfer of glucose across the plasma membrane.
Immunogen
GLUT2 antibody was raised in rabbit using a 14 amino acid peptide from human GT22 as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-GLUT2 antibody
Rabbit polyclonal GLUT2 antibody
Product Categories/Family for anti-GLUT2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
57,107 Da
NCBI Official Full Name
GLUT2, partial
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 2
NCBI Official Symbol
Slc2a2
NCBI Official Synonym Symbols
Glut2; Glut-2; AI266973
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 2
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 2
UniProt Gene Name
Slc2a2
UniProt Synonym Gene Names
Glut-2; Glut2; GLUT-2
UniProt Entry Name
GTR2_MOUSE

Uniprot Description

GLUT2: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family. Present at high levels in the plasma membrane of pancreatic b-cells where it initiates the first step in glucose-stimulated insulin secretion, a glucose metabolism-dependent signaling mechanism. May mediate the bidirectional transfer of glucose across the plasma membrane of hepatocytes. May also participate with the Na( +2)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Required for glucose sensitivity in the hypothalamus and brain stem. Involved in the control of food intake and stimulation of glucose uptake by peripheral tissues.

Protein type: Transporter, SLC family; Membrane protein, integral; Transporter; Membrane protein, multi-pass

Cellular Component: membrane; basolateral plasma membrane; brush border membrane; cytoplasm; plasma membrane; integral to membrane; cytosol; endosome; brush border

Molecular Function: D-glucose transmembrane transporter activity; dehydroascorbic acid transporter activity; transporter activity; glucose transmembrane transporter activity; transmembrane transporter activity; substrate-specific transmembrane transporter activity; insulin receptor binding

Biological Process: carbohydrate utilization; transport; carbohydrate transport; glucose transport; transmembrane transport

Research Articles on GLUT2

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Product Notes

The GLUT2 slc2a2 (Catalog #AAA534294) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GLUT2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GLUT2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). ELISA: 0.5-1 ug/ml IHC: 2-10 ug/ml WB: 1-10 ug/ml. Researchers should empirically determine the suitability of the GLUT2 slc2a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLUT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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