Western Blot (WB)
(Western blot analysis of AIRE expression in Jurkat (A); mouse lung (B); rat lung (C) whole cell lysates.)
Rabbit AIRE Polyclonal Antibody | anti-AIRE antibody
AIRE Antibody
Gene Names
AIRE; APS1; APSI; PGA1; AIRE1; APECED
Applications
Western Blot, Immunofluorescence, Immunocytochemistry
Purity
Immunogen Affinity Chromatography
Synonyms
AIRE; Polyclonal Antibody; AIRE Antibody; Purified Polyclonal AIRE Antibody; Polyclonal AIRE antibody; Anti-AIRE antibody; APECED antibody; Autoimmune regulator antibody; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein antibody; APECED protein antibody; anti-AIRE antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of AIRE protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
515
Applicable Applications for anti-AIRE antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes
WB: 1:500-1:1000
IF: 1:100-1:500
ICC: 1:100-1:500
IF: 1:100-1:500
ICC: 1:100-1:500
Immunogen
AIRE antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the center region of human AIRE as the immunogen
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of AIRE expression in Jurkat (A); mouse lung (B); rat lung (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of AIRE expression in Jurkat (A); mouse lung (B); rat lung (C) whole cell lysates.)
Related Product Information for anti-AIRE antibody
AIRE is a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus.
Product Categories/Family for anti-AIRE antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
AIRE
NCBI Official Synonym Full Names
autoimmune regulator
NCBI Official Symbol
AIRE
NCBI Official Synonym Symbols
APS1; APSI; PGA1; AIRE1; APECED
NCBI Protein Information
autoimmune regulator
Protein Family
NCBI Description
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
Research Articles on AIRE
Similar Products
Product Notes
The AIRE (Catalog #AAA5316066) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's AIRE can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC). WB: 1:500-1:1000 IF: 1:100-1:500 ICC: 1:100-1:500. Researchers should empirically determine the suitability of the AIRE for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AIRE, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
