Western Blot (WB)
(Western blot analysis of Presenilin 1 expression in HL60 (A); HeLa (B); SKNMC (C); COS7 (D) whole cell lysates.)
Rabbit Presenilin 1 Polyclonal Antibody | anti-PSNL1 antibody
Presenilin 1 Antibody
Gene Names
PSEN1; PS-1; presenilin-1
Applications
Western Blot
Purity
Immunogen Affinity Chromatography
Synonyms
Presenilin 1; Polyclonal Antibody; Presenilin 1 Antibody; Purified Polyclonal Presenilin 1 Antibody; Polyclonal Presenilin 1 antibody; Anti-Presenilin 1 antibody; AD3 antibody; PS1 antibody; PSNL1 antibody; Presenilin-1 antibody; PS-1 antibody; Protein S182 antibody; anti-PSNL1 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of Presenilin 1 protein
Purity/Purification
Immunogen Affinity Chromatography
Form/Format
Supplied in liquid form in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3 with 30% Glycerol and 0.01% Sodium Azide
Sequence Length
468
Applicable Applications for anti-PSNL1 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:1000
Immunogen
Presenilin 1 antibody was raised in Rabbit using a KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Presenilin 1 as the immunogen
Cross-Reactivity
Monkey
Preparation and Storage
Store at 4 degree C for short term storage. For long term, aliquot and store at -20 degree C. Avoid repeat freeze/thaw cycles.
Western Blot (WB)
(Western blot analysis of Presenilin 1 expression in HL60 (A); HeLa (B); SKNMC (C); COS7 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Presenilin 1 expression in HL60 (A); HeLa (B); SKNMC (C); COS7 (D) whole cell lysates.)
Related Product Information for anti-PSNL1 antibody
Presenilin 1 is one of the four core proteins in presenilin complex, which mediate the regulated proteolytic events of several proteins in the cell, including gamma secretase. Gamma-secretase is considered to play a very important role in generation of beta amyloid, accumulation of which is related to the onset of Alzheimer's Disease, from the beta-amyloid precursor protein.
Product Categories/Family for anti-PSNL1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
presenilin-1
NCBI Official Synonym Full Names
presenilin 1
NCBI Official Symbol
PSEN1
NCBI Official Synonym Symbols
PS-1; presenilin-1
NCBI Protein Information
presenilin-1
UniProt Protein Name
Presenilin-1
UniProt Gene Name
PSEN1
UniProt Synonym Gene Names
PS-1
Uniprot Description
Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins.
Research Articles on PSNL1
Similar Products
Product Notes
The PSNL1 psen1 (Catalog #AAA5314897) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Presenilin 1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:1000. Researchers should empirically determine the suitability of the PSNL1 psen1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Presenilin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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