Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using mTOR antibody (Ser2448))
Rabbit mTOR Polyclonal Antibody | anti-mTOR antibody
mTOR Antibody (Ser2448)
Applications
Immunohistochemistry
Purity
Affinity Chromatography
Synonyms
mTOR; Polyclonal Antibody; mTOR Antibody (Ser2448); Rabbit Polyclonal mTOR Antibody (Ser2448); Polyclonal mTOR antibody; Anti-mTOR antibody; FK506 binding protein 12-rapamycin associated protein 1 antibody; FK506 binding protein 12-rapamycin associated protein 2 antibody; FK506-binding protein 12-rapamycin complex-associated protein 1 antibody; FKBP-rapamycin associated protein antibody; FKBP12-rapamycin complex-associated protein antibody; FKBP12-rapamycin complex-associated protein 1 antibody; FLJ44809 antibody; FRAP antibody; FRAP1 antibody; FRAP2 antibody; Mammalian target of rapamycin antibody; mechanistic target of rapamycin (serine/threonine kinase) antibody; mTOR antibody; RAFT1 antibody; rapamycin and FKBP12 target 1 antibody; rapamycin associated protein FRAP2 antibody; Rapamycin target protein 1 antibody; RAPT1 antibody; Serine/threonine-protein kinase mTOR antibody; anti-mTOR antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Specificity
mTOR antibody (Ser2448) detects endogenous levels of mTOR only when phosphorylated at serine 2448
Purity/Purification
Affinity Chromatography
Form/Format
Supplied in PBS buffer (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% Sodium Azide and 50% Glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
445
Applicable Applications for anti-mTOR antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
mTOR antibody was raised in Rabbit using a synthesized phosphopeptide derived from human mTOR around the phosphorylation site of serine 2448 (T-D-SP-Y-S) as the immunogen.
Cross-Reactivity
Mouse, Rat
Preparation and Storage
Store at -20 degree C in small aliquots. Avoid repeat freeze/thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using mTOR antibody (Ser2448))
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using mTOR antibody (Ser2448))
Related Product Information for anti-mTOR antibody
mTOR is an atypical kinase belonging to the PIKK family of kinases. Is the catalytic subunit of two protein complexes, mTORC1 and mTORC2. mTORC1 activates S6K and inactivates 4E-BP1, up-regulating protein synthesis. mTORC1 contains Raptor, a positive regulatory subunit and scaffold for recruiting substrates, two negative regulators, PRAS40 and DEPTOR, and mLST8; it is a target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Product Categories/Family for anti-mTOR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI Official Full Name
mTOR, partial
Protein Family
Similar Products
Product Notes
The mTOR (Catalog #AAA5313647) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's mTOR can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the mTOR for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "mTOR, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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