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Mouse CEA Monoclonal Antibody | anti-CEA antibody

CEA antibody (in PBS)

Gene Names
CEACAM6; NCA; CEAL; CD66c
Applications
ELISA
Synonyms
CEA; Monoclonal Antibody; CEA antibody (in PBS); Monoclonal CEA; Anti-CEA; Carcinoembryonic Antigen; anti-CEA antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M111146
Form/Format
Chromatographically purified, supplied in PBS buffer, pH 7.5 with 0.05% NaN3
Concentration
10.2 mg/ml (varies by lot)
Applicable Applications for anti-CEA antibody
ELISA (EIA)
Application Notes
Can be used as a detection antibody in an ELISA assay using MBS530175 as the capture antibody. Optimal conditions to be determined by end user.
Immunogen
Purified natural CEA
Cross Reactivity
CEA 100%
Affinity Constant
~5.0 x 1010 L/M
Biological Significance
Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Preparation and Storage
Store at 4°C
Related Product Information for anti-CEA antibody
Mouse monoclonal CEA antibody
Product Categories/Family for anti-CEA antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Official Full Name
carcinoembryonic antigen, partial
NCBI Official Synonym Full Names
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
NCBI Official Symbol
CEACAM6
NCBI Official Synonym Symbols
NCA; CEAL; CD66c
NCBI Protein Information
carcinoembryonic antigen-related cell adhesion molecule 6
UniProt Protein Name
Carcinoembryonic antigen-related cell adhesion molecule 6
Protein Family
UniProt Gene Name
CEACAM6
UniProt Synonym Gene Names
NCA
UniProt Entry Name
CEAM6_HUMAN

NCBI Description

This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq, Apr 2014]

Uniprot Description

CEACAM6: Belongs to the immunoglobulin superfamily. CEA family

Protein type: Membrane protein, integral; Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding

Biological Process: cell-cell signaling; signal transduction; blood coagulation; leukocyte migration

Research Articles on CEA

Similar Products

Product Notes

The CEA ceacam6 (Catalog #AAA530761) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's CEA can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Can be used as a detection antibody in an ELISA assay using MBS530175 as the capture antibody. Optimal conditions to be determined by end user. Researchers should empirically determine the suitability of the CEA ceacam6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CEA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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