IL4 active protein
IL4 protein
Purity
> 98% pureIL4 protein was purified using a a proprietary chromatographic technique.
Synonyms
IL4; IL4 protein; Pitrakinra protein; IL-4 protein; B cell stimulating factor protein; Lymphocyte stimulatory factor 1 protein; BSF-1 protein; BCGF protein; Binetrakin protein; BCDF protein; IL-4; MGC79402 protein; IL 4; IL 4 protein; IL4 active protein
Host
Mouse
Purity/Purification
> 98% pure
IL4 protein was purified using a a proprietary chromatographic technique.
IL4 protein was purified using a a proprietary chromatographic technique.
Form/Format
Supplied in lyophilized form with no additives
Sequence Length
153
Protein Type
Recombinant
Biological Significance
IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy.
Bioactivity
The ED50 determined by the dose-dependent stimulation of the proliferation of murine HT-2 cells is < 20 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg
Endotoxin Levels
<0.1 ng/ug
Expression System
E Coli
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for IL4 active protein
Purified recombinant Mouse IL4 protein
Product Categories/Family for IL4 active protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
13.5 kDa
NCBI Official Full Name
IL4, partial
Protein Family
Similar Products
Product Notes
The IL4 (Catalog #AAA5303911) is an Active Protein produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "IL4, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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