FGF16 recombinant protein

FGF16

Cat. Num. AAA517003

• Gene Names: FGF16; MF4; FGF-16
• Applications: Cell Assay
• Synonyms: FGF16; Fibroblast Growth Factor 16; FGF-16; FGFG; Recombinant Human Fibroblast Growth Factor (FGF16); FGF16 recombinant protein

• Host: E Coli

• Applicable Applications for FGF16 recombinant protein: Cell Assay
• Species: Human
• Endotoxin Level: <1.0EU/ug of recombinant protein as determined by the LAL method.
• Preparation and Storage: The lyophilized protein is stable for at least one year from date of receipt at -70 degree C. Upon reconstitution, this cytokine can be stored in working aliquots at 2 degree -8 degree C for one month, or at -20 degree C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Testing Data

SDS-Page

(Purity: Recombinant Human FGF16 resolved on a 15% SDS-PAGE gel under reducing conditions and stained with Coomassie Brilliant Blue G-250)

Related Product Information for FGF16 recombinant protein

Recombinant Human FGF16 was expressed in E Coli cells. The protein accession number is O43320
FGF16 is a member of the FGF family and is a heparin binding growth factor. FGF16 plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. It also is important for development of the nervous system. FGF16 signals though FGFR 2c and 3c.

Product Categories/Family for FGF16 recombinant protein

Growth Factors

NCBI and Uniprot Product Information

• NCBI GI #: 4503691
• NCBI GeneID: 8823
• NCBI Accession #: NP_003859.1
• NCBI GenBank Nucleotide #: NM_003868.2
• UniProt Accession #: O43320
• Molecular Weight: 23,759 Da
• NCBI Official Full Name: fibroblast growth factor 16
• NCBI Official Synonym Full Names: fibroblast growth factor 16
• NCBI Official Symbol: FGF16
• NCBI Official Synonym Symbols: MF4; FGF-16
• NCBI Protein Information: fibroblast growth factor 16
• UniProt Protein Name: Fibroblast growth factor 16
• Protein Family: Fibroblast growth factor
• UniProt Gene Name: FGF16
• UniProt Synonym Gene Names: FGF-16
• UniProt Entry Name: FGF16_HUMAN

Uniprot Description

FGF16: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation, and is required for normal cardiomyocyte proliferation and heart development. Belongs to the heparin-binding growth factors family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: Xq13

Cellular Component: extracellular region; extracellular space

Molecular Function: 1-phosphatidylinositol-3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity

Biological Process: cell-cell signaling; fibroblast growth factor receptor signaling pathway; MAPKKK cascade; metabolic process; organ morphogenesis; phosphoinositide-mediated signaling; regulation of endothelial cell proliferation; regulation of MAP kinase activity; regulation of phosphoinositide 3-kinase cascade; response to temperature stimulus; signal transduction

Disease: Metacarpal 4-5 Fusion