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Western Blot (WB) (Western blot analysis using EGF mAb against EGF (AA)

Mouse anti-Human EGF Monoclonal Antibody | anti-EGF antibody

Anti-EGF Mouse mAb

Gene Names
EGF; URG; HOMG4
Reactivity
Human
Applications
Western Blot, Immunocytochemistry
Synonyms
EGF; Monoclonal Antibody; Anti-EGF Mouse mAb; URG; HOMG4; anti-EGF antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
4E11
Form/Format
Ascitic fluid containing 0.03% sodium azide.
Sequence Length
168
Applicable Applications for anti-EGF antibody
Western Blot (WB), Immunocytochemistry (ICC)
Immunogen
Purified recombinant fragment of human EGF expressed in E Coli.

Western Blot (WB)

(Western blot analysis using EGF mAb against EGF (AA)

Western Blot (WB) (Western blot analysis using EGF mAb against EGF (AA)

Immunofluorescence (IF)

(Immunofluorescence analysis of NIH/3T3 cells using EGF mouse mAb (green). Blue)

Immunofluorescence (IF) (Immunofluorescence analysis of NIH/3T3 cells using EGF mouse mAb (green). Blue)
Related Product Information for anti-EGF antibody
Entrez Summary: Epidermal growth factor has a profound effect on the differentiation of specific cells in vivo and is a potent mitogenic factor for a variety of cultured cells of both ectodermal and mesodermal origin. The EGF precursor is believed to exist as a membrane-bound molecule which is proteolytically cleaved to generate the 53-amino acid peptide hormone that stimulates cells to divide.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
134
NCBI Official Full Name
EGF, partial
NCBI Official Synonym Full Names
epidermal growth factor
NCBI Official Symbol
EGF
NCBI Official Synonym Symbols
URG; HOMG4
NCBI Protein Information
pro-epidermal growth factor
UniProt Protein Name
Pro-epidermal growth factor
UniProt Gene Name
EGF
UniProt Synonym Gene Names
EGF

NCBI Description

This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]

Uniprot Description

EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).

Research Articles on EGF

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Product Notes

The EGF egf (Catalog #AAA475987) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Anti-EGF Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EGF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the EGF egf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EGF, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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