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Western Blot (WB) (Western Blot analysis of SEC11A in TM4 cell, Mouse kidney tissue lysates in order using SEC11A Rabbit pAb at dilution 1/250)

Rabbit SEC11A Polyclonal Antibody | anti-SEC11A antibody

SEC11A Rabbit pAb

Gene Names
SEC11A; SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
SEC11A; Polyclonal Antibody; SEC11A Rabbit pAb; SEC11 homolog A; signal peptidase complex subunit; SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik; anti-SEC11A antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.66mg/ml (varies by lot)
Applicable Applications for anti-SEC11A antibody
Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Fusion protein of human SEC11A
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of SEC11A in TM4 cell, Mouse kidney tissue lysates in order using SEC11A Rabbit pAb at dilution 1/250)

Western Blot (WB) (Western Blot analysis of SEC11A in TM4 cell, Mouse kidney tissue lysates in order using SEC11A Rabbit pAb at dilution 1/250)
Related Product Information for anti-SEC11A antibody
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,988 Da
NCBI Official Full Name
signal peptidase complex catalytic subunit SEC11A isoform 2
NCBI Official Synonym Full Names
SEC11 homolog A (S. cerevisiae)
NCBI Official Symbol
SEC11A
NCBI Official Synonym Symbols
SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik
NCBI Protein Information
signal peptidase complex catalytic subunit SEC11A; endopeptidase SP18; SEC11-like protein 1; SPase 18 kDa subunit; signal peptidase complex (18kD); microsomal signal peptidase 18 kDa subunit
UniProt Protein Name
Signal peptidase complex catalytic subunit SEC11A
Protein Family
UniProt Gene Name
SEC11A
UniProt Synonym Gene Names
SEC11L1; SPC18; SPCS4A; SPase 18 kDa subunit
UniProt Entry Name
SC11A_HUMAN

NCBI Description

This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Dec 2012]

Uniprot Description

SEC11A: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the peptidase S26B family.

Protein type: EC 3.4.21.89; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 15q25.3

Cellular Component: endoplasmic reticulum membrane; integral to membrane

Molecular Function: serine-type peptidase activity

Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; signal peptide processing; gene expression; proteolysis; regulation of insulin secretion

Research Articles on SEC11A

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Product Notes

The SEC11A sec11a (Catalog #AAA4759214) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SEC11A Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SEC11A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the SEC11A sec11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SEC11A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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