Human Dynamin 2 (DNM2) ELISA Kit | DNM2 elisa kit

Human Dynamin 2 (DNM2) ELISA Kit

Cat. Num. AAA455437

• Gene Names: DNM2; DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB
• Reactivity: Human
• Synonyms: Dynamin 2 (DNM2); Human Dynamin 2 (DNM2) ELISA Kit; SLC2A1; SLC2-A1; GLUT; Solute Carrier Family 2 Member 1; Facilitated Glucose Transporter; DNM2 elisa kit

• Reactivity: Human
• Sequence Length: 870

• Samples: Tissue homogenates, cell lysates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.106ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

NCBI and Uniprot Product Information

• NCBI GI #: 56549121
• NCBI GeneID: 1785
• NCBI Accession #: NP_001005360.1
• NCBI GenBank Nucleotide #: NM_001005360.2
• UniProt Accession #: P50570; Q5I0Y0; Q7Z5S3; Q9UPH4; A8K1B6; E7EV30; E9PEQ4; K7ESI9
• Molecular Weight: 97,977 Da
• NCBI Official Full Name: dynamin-2 isoform 1
• NCBI Official Synonym Full Names: dynamin 2
• NCBI Official Symbol: DNM2
• NCBI Official Synonym Symbols: DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB
• NCBI Protein Information: dynamin-2
• UniProt Protein Name: Dynamin-2
• Protein Family: Dynamin
• UniProt Gene Name: DNM2
• UniProt Synonym Gene Names: DYN2

NCBI Description

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]

Uniprot Description

Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (). Plays an important role in vesicular trafficking processes, in particular endocytosis. Involved in cytokinesis (PubMed:12498685). Regulates maturation of apoptotic cell corpse-containing phagosomes by recruiting PIK3C3 to the phagosome membrane ().