Rat Linker For Activation Of T-Cell (LAT) ELISA Kit | LAT elisa kit

Rat Linker For Activation Of T-Cell (LAT) ELISA Kit

Cat. Num. AAA450016

• Reactivity: Rat
• Synonyms: Linker For Activation Of T-Cell (LAT); Rat Linker For Activation Of T-Cell (LAT) ELISA Kit; LAT1; Pp36; Linker Of Activated T Cells; Linker for activation of T-cells family member 1; 36 kDa phospho-tyrosine adapter protein; LAT elisa kit

• Reactivity: Rat
• Sequence Length: 241

• Samples: Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
• Assay Type: Sandwich
• Detection Range: 0.156-10ng/mL
• Sensitivity: 0.036ng/mL
• Intra Assay: CV<10%
• Inter Assay: CV<12%
• Preparation and Storage: For unopened kit, all reagents should be kept according to the labels on vials. The TMB Substrate, Wash Buffer, Stop Solution should be stored at 4 degree C. All others should be stored at -20 degree C.

Typical Standard Curve/Testing Data

NCBI and Uniprot Product Information

• NCBI GI #: 13540669
• NCBI GeneID: 81511
• NCBI Accession #: NP_110480.1
• NCBI GenBank Nucleotide #: NM_030853.1
• UniProt Accession #: O70601
• Molecular Weight: 26,193 Da
• NCBI Official Full Name: linker for activation of T-cells family member 1
• NCBI Official Synonym Full Names: linker for activation of T cells
• NCBI Official Symbol: Lat
• NCBI Protein Information: linker for activation of T-cells family member 1
• UniProt Protein Name: Linker for activation of T-cells family member 1
• Protein Family: L-lysine-epsilon aminotransferase
• UniProt Gene Name: Lat
• UniProt Synonym Gene Names: pp36

NCBI Description

an adaptor protein; involved in signalling after T-cell activation [RGD, Feb 2006]

Uniprot Description

Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules ().