ELISA (EIA)
Mouse anti-Human Calcitonin Monoclonal Antibody | anti-CT antibody
Calcitonin [3L7] Mouse mAb
Gene Names
CALCA; CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
Reactivity
Human
Applications
ELISA
Synonyms
Calcitonin; Monoclonal Antibody; Calcitonin [3L7] Mouse mAb; anti-CT antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2b
Sequence Length
141
Applicable Applications for anti-CT antibody
ELISA (EIA)
Application Notes
ELISA: 1:50000-1:1000
Source Note
This monoclonal antibody is produced by immunizing mice with a Synthetic peptide corresponding to the amino acids 16-32 of human Calcitonin, conjugated to a high molecular weight carrier
Preparation and Storage
Stored at -20 degree C or below until use. Avoid repeated freezing and thawing cycles.
ELISA (EIA)
ELISA (EIA)
Related Product Information for anti-CT antibody
The most prominent clinical syndrome associated with a disordered hypersecretion of Calcitonin (CT) is medullary carcinoma of the thyroid (MTC). MTC is a tumor of the Calcitonin producing C-cells of the thyroid gland. Although MTC is rare, comprising 5 -10% of all thyroid cancer, it is often fatal. Further, it leant itself to be identified early by serum Calcitonin and total cure for early sub-clinical disease is possible. Neoplastic disorders of other neuroendocrine cells can also elevate Calcitonin. The best example is small cell lung cancer. Other tumors such as carcinoids and islet cell tumors of the pancreas can also result in elevated serum Calcitonin. Increases in serum Calcitonin has also been noted in both acute and chronic renal failure, hypercalciuria and hypercalcemia.
Product Categories/Family for anti-CT antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,535 Da
NCBI Official Full Name
calcitonin isoform CT preproprotein
NCBI Official Synonym Full Names
calcitonin related polypeptide alpha
NCBI Official Symbol
CALCA
NCBI Official Synonym Symbols
CT; KC; PCT; CGRP; CALC1; CGRP1; CGRP-I
NCBI Protein Information
calcitonin; calcitonin gene-related peptide 1
UniProt Protein Name
Calcitonin
Protein Family
UniProt Gene Name
CALCA
UniProt Synonym Gene Names
CALC1; CCP
NCBI Description
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
Uniprot Description
Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Research Articles on CT
Similar Products
Product Notes
The CT calca (Catalog #AAA435312) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Calcitonin [3L7] Mouse mAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Calcitonin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). ELISA: 1:50000-1:1000. Researchers should empirically determine the suitability of the CT calca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Calcitonin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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