POU2F2 / OCT2 Blocking Peptide | POU2F2 blocking peptide
POU2F2 / OCT2 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Uniprot Description
Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 19q13.2
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: protein domain specific binding; sequence-specific DNA binding; transcription factor activity
Biological Process: cell maturation; humoral immune response; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription from RNA polymerase II promoter; snRNA transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter
Research Articles on POU2F2
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Product Notes
The POU2F2 pou2f2 (Catalog #AAA427865) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The POU2F2 / OCT2 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Pig and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-SPTGPSTK IKAED. It is sometimes possible for the material contained within the vial of "POU2F2 / OCT2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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