INDOL1 Blocking Peptide | IDO2 blocking peptide
INDOL1 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
Along with the enzymes encoded by the INDO (MIM 147435) and TDO2 (MIM 191070) genes, the enzyme encoded by the INDOL1 gene metabolizes tryptophan in the kynurenine pathway (Ball et al., 2007 [PubMed 17499941]).[supplied by OMIM, Feb 2011]
Uniprot Description
INDOL1: Catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan catabolism. Belongs to the indoleamine 2,3-dioxygenase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Oxidoreductase; Amino Acid Metabolism - tryptophan; EC 1.13.11.-
Chromosomal Location of Human Ortholog: 8p11.21
Cellular Component: cytoplasm; cytosol
Molecular Function: heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; tryptophan 2,3-dioxygenase activity
Biological Process: immune system process; tryptophan catabolic process; tryptophan catabolic process to kynurenine
Research Articles on IDO2
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Product Notes
The IDO2 ido2 (Catalog #AAA425839) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The INDOL1 Immunizing Peptide reacts with Human, Dog, Cow and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-RDKTLESI LHPR. It is sometimes possible for the material contained within the vial of "INDOL1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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