NEBL / nebulette Blocking Peptide | NEBL blocking peptide
NEBL / nebulette Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a nebulin like protein that is abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. This protein may be involved in cardiac myofibril assembly. A shorter isoform of this protein termed LIM nebulette is expressed in non-muscle cells and may function as a component of focal adhesion complexes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Uniprot Description
NEBL: Binds to actin and plays an important role in the assembly of the Z-disk. Isoform 2 might play a role in the assembly of focal adhesion. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Actin-binding
Chromosomal Location of Human Ortholog: 10p12
Cellular Component: I band; stress fiber; Z disc
Molecular Function: actin filament binding; cytoskeletal protein binding; filamin binding; protein binding; structural constituent of muscle; tropomyosin binding
Research Articles on NEBL
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Product Notes
The NEBL nebl (Catalog #AAA425545) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The NEBL / nebulette Immunizing Peptide reacts with Human, Mouse, Dog and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-ELQRLKRT QE. It is sometimes possible for the material contained within the vial of "NEBL / nebulette, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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