Western Blot (WB)
((1ug/ml) staining of Human Erythrocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat NAT1 Polyclonal Antibody | anti-NAT1 antibody
Goat anti-NAT1 (aa272-286) Antibody
Western Blot: Approx 30kDa band observed in Human Erythrocytes lysates (calculated MW of 33.9kDa according to NP_000653.3). Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((1ug/ml) staining of Human Erythrocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of Human Erythrocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This gene is one of two arylamine N-acetyltransferase (NAT) genes in the human genome, and is orthologous to the mouse and rat Nat2 genes. The enzyme encoded by this gene catalyzes the transfer of an acetyl group from acetyl-CoA to various arylamine and hydrazine substrates. This enzyme helps metabolize drugs and other xenobiotics, and functions in folate catabolism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
NAT1: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.
Protein type: Secondary Metabolites Metabolism - caffeine; EC 2.3.1.5; Xenobiotic Metabolism - drug metabolism - other enzymes; Acetyltransferase
Chromosomal Location of Human Ortholog: 8p22
Cellular Component: cytosol
Molecular Function: arylamine N-acetyltransferase activity
Biological Process: xenobiotic metabolic process
Research Articles on NAT1
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Product Notes
The NAT1 nat1 (Catalog #AAA423267) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-NAT1 (aa272-286) Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's NAT1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 128000. Western Blot: Approx 30kDa band observed in Human Erythrocytes lysates (calculated MW of 33.9kDa according to NP_000653.3). Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the NAT1 nat1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: NISLQRKLVP KHGDR. It is sometimes possible for the material contained within the vial of "NAT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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