Western Blot (WB)
((1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat syndecan 1/CD138 Polyclonal Antibody | anti-SDC1 antibody
Goat anti-syndecan 1/CD138 Antibody
Western Blot: Approx 37kDa band observed in lysates of cell line HepG2 and of Gastrointensinal cancer and Spinal Cord cancer (calculated MW of 32.5kDa according to NP_002988.3). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 1-3ug/ml.
Western Blot (WB)
((1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((1ug/ml) staining of HepG2 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]
Uniprot Description
syndecan-1: Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix. Belongs to the syndecan proteoglycan family.
Protein type: Membrane protein, integral; Extracellular matrix; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 2p24.1
Cellular Component: cell surface; cytoplasm; external side of plasma membrane; focal adhesion; Golgi lumen; integral to plasma membrane; lysosomal lumen; plasma membrane; protein complex
Molecular Function: glycoprotein binding; protein binding; protein C-terminus binding
Biological Process: cell migration; glycosaminoglycan biosynthetic process; glycosaminoglycan catabolic process; glycosaminoglycan metabolic process; inflammatory response; lipoprotein metabolic process; myoblast development; odontogenesis; response to calcium ion; response to cAMP; response to glucocorticoid stimulus; response to hydrogen peroxide; response to toxin; retinoid metabolic process; Sertoli cell development; striated muscle cell development; ureteric bud development; Wnt receptor signaling pathway through beta-catenin; wound healing
Research Articles on SDC1
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Product Notes
The SDC1 sdc1 (Catalog #AAA423223) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-syndecan 1/CD138 Antibody reacts with Tested: Human; Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's syndecan 1/CD138 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Approx 37kDa band observed in lysates of cell line HepG2 and of Gastrointensinal cancer and Spinal Cord cancer (calculated MW of 32.5kDa according to NP_002988.3). The observed molecular weight corresponds to the glycosylated form. Recommended concentration: 1-3ug/ml. Researchers should empirically determine the suitability of the SDC1 sdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: REQEATPRPR ETTQ. It is sometimes possible for the material contained within the vial of "syndecan 1/CD138, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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