Goat MUC16/CA125 Polyclonal Antibody | anti-MUC16 antibody

Goat anti-MUC16/CA125 Antibody

Cat. Num. AAA422348

• Gene Names: MUC16; CA125
• Reactivity: Expected from sequence similarity: Human
• Applications: ELISA
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: MUC16/CA125; Polyclonal Antibody; Goat anti-MUC16/CA125 Antibody; MUC16; mucin 16; cell surface associated; CA125; FLJ14303; CA125 ovarian cancer antigen; CA125 antibody; CA125 ovarian cancer antigen antibody; FLJ14303 antibody; mucin 16 antibody; cell surface associated antibody; MUC16 antibody; MUC16 / CA125; anti-MUC16 antibody

• Host: Goat
• Reactivity: Expected from sequence similarity: Human
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: PQNLSIRGEYQIN
• Sequence Length: 14507

• Applicable Applications for anti-MUC16 antibody: Peptide ELISA (EIA)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 16000.; Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as large as the calculated size of 1519kDa according to NP_078966.2. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
• Immunogen: Peptide with sequence C-PQNLSIRGEYQIN, from the C Terminus of the protein sequence according to NP_078966.2.
• Epitope: C Terminus
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

• NCBI GI #: 83367077
• NCBI GeneID: 94025
• NCBI Accession #: NP_078966.2
• NCBI GenBank Nucleotide #: NM_024690.2
• Molecular Weight: 1,519,175 Da
• NCBI Official Full Name: mucin-16
• NCBI Official Synonym Full Names: mucin 16, cell surface associated
• NCBI Official Symbol: MUC16
• NCBI Official Synonym Symbols: CA125
• NCBI Protein Information: mucin-16
• UniProt Protein Name: Mucin-16
• Protein Family: Mucin
• UniProt Gene Name: MUC16
• UniProt Synonym Gene Names: CA-125
• UniProt Entry Name: MUC16_HUMAN

Uniprot Description

MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Protein type: Membrane protein, integral; Membrane protein, peripheral; Cell adhesion

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; integral to membrane; plasma membrane; vesicle

Molecular Function: protein binding

Biological Process: cell adhesion; O-glycan processing