Goat X-arrestin/arrestin 3 Polyclonal Antibody | anti-ARR3 antibody
Goat anti-X-arrestin/arrestin 3 Antibody
Western Blot: Not yet tested due to unavailability of retinal tissue. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the product is an aspiring grade product.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]
Uniprot Description
ARR3: May play a role in an as yet undefined retina-specific signal transduction. Could binds to photoactivated-phosphorylated red/green opsins. Belongs to the arrestin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: Xcen-q21
Cellular Component: cytoplasm; photoreceptor inner segment; photoreceptor outer segment; synapse
Molecular Function: opsin binding; phosphoprotein binding; protein binding; protein domain specific binding
Biological Process: endocytosis; regulation of protein amino acid phosphorylation; signal transduction; visual perception
Research Articles on ARR3
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Product Notes
The ARR3 arr3 (Catalog #AAA422109) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-X-arrestirrestin 3 Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's X-arrestirrestin 3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 1000. Western Blot: Not yet tested due to unavailability of retinal tissue. At this stage we are dependent on researchers in the field for further characterization of this product. Therefore we cannot recommend an optimal concentration and the product is an aspiring grade product. Researchers should empirically determine the suitability of the ARR3 arr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: RKGEEESQKA VE. It is sometimes possible for the material contained within the vial of "X-arrestin/arrestin 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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