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Goat AIFM3 Polyclonal Antibody | anti-AIFM3 antibody

Goat anti-AIFM3 Antibody

Gene Names
AIFM3; AIFL
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
AIFM3; Polyclonal Antibody; Goat anti-AIFM3 Antibody; apoptosis-inducing factor; mitochondrion-associated; 3; AIFL; FLJ30473; apoptosis-inducing factor like; AIFL antibody; apoptosis-inducing factor like antibody; 3 antibody; FLJ30473 antibody; AIFM3 antibody; anti-AIFM3 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
TARHFHTEERLSTPH
Sequence Length
605
Applicable Applications for anti-AIFM3 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Preliminary experiments in Human Colon, Kidney and Liver lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Immunogen
Peptide with sequence C-TARHFHTEERLSTPH, from the internal region of the protein sequence according to NP_653305.1; NP_001018070.1; NP_001139760.1.
Epitope
Internal region
Note
This antibody is expected to recognize all isoforms (NP_653305.1; NP_001018070.1, NP_001139760.1).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
Molecular Weight
65,966 Da
NCBI Official Full Name
apoptosis-inducing factor 3 isoform 1
NCBI Official Synonym Full Names
apoptosis inducing factor, mitochondria associated 3
NCBI Official Symbol
AIFM3
NCBI Official Synonym Symbols
AIFL
NCBI Protein Information
apoptosis-inducing factor 3
UniProt Protein Name
Apoptosis-inducing factor 3
Protein Family
UniProt Gene Name
AIFM3
UniProt Synonym Gene Names
AIFL
UniProt Entry Name
AIFM3_HUMAN

Uniprot Description

AIFM3: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. Belongs to the FAD-dependent oxidoreductase family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Endoplasmic reticulum; Oxidoreductase; Apoptosis; Mitochondrial

Chromosomal Location of Human Ortholog: 22q11.21

Cellular Component: endoplasmic reticulum; mitochondrial inner membrane; mitochondrion; nucleus

Molecular Function: 2 iron, 2 sulfur cluster binding; FAD binding; metal ion binding; oxidoreductase activity

Biological Process: cell redox homeostasis

Research Articles on AIFM3

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Product Notes

The AIFM3 aifm3 (Catalog #AAA421874) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-AIFM3 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's AIFM3 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 64000. Western Blot: Preliminary experiments in Human Colon, Kidney and Liver lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Researchers should empirically determine the suitability of the AIFM3 aifm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TARHFHTEER LSTPH. It is sometimes possible for the material contained within the vial of "AIFM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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