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Western Blot (WB)

Rabbit Neurogenin 2 Polyclonal Antibody | anti-NEUROG2 antibody

Anti-Neurogenin 2 Antibody

Gene Names
NEUROG2; NGN2; Atoh4; ngn-2; Math4A; bHLHa8
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity purified
Synonyms
Neurogenin 2; Polyclonal Antibody; Anti-Neurogenin 2 Antibody; anti-NEUROG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
2370
Applicable Applications for anti-NEUROG2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA titer: 1:80,000
Western blot analysis: 1:200-1000
Optimal dilutions/concentrations should be determined by the end user.
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Synthetic peptide conjugated to KLH
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-NEUROG2 antibody
Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells
References
(1)McCormick,M.B.,Tamimi,R.M.,Snider,L.,,et,al NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family Mol. Cell. Biol. 1996;16(10): 5792-5800.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,621 Da
NCBI Official Full Name
Homo sapiens neurogenin 2 (NEUROG2), mRNA
NCBI Official Synonym Full Names
neurogenin 2
NCBI Official Symbol
NEUROG2
NCBI Official Synonym Symbols
NGN2; Atoh4; ngn-2; Math4A; bHLHa8
NCBI Protein Information
neurogenin-2; class A basic helix-loop-helix protein 8; protein atonal homolog 4
UniProt Protein Name
Neurogenin-2
Protein Family
UniProt Gene Name
NEUROG2
UniProt Entry Name
NGN2_HUMAN

NCBI Description

This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]

Uniprot Description

neurogenin 2: Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: nucleus

Molecular Function: protein dimerization activity; sequence-specific DNA binding

Biological Process: axon guidance; cell fate commitment; transcription, DNA-dependent; forebrain development; cell maturation; neuron migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; central nervous system neuron development

Research Articles on NEUROG2

Similar Products

Product Notes

The NEUROG2 neurog2 (Catalog #AAA416140) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Neurogenin 2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Neurogenin 2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA titer: 1:80,000 Western blot analysis: 1:200-1000 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the NEUROG2 neurog2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neurogenin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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