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Western Blot (WB)

Rabbit SERPINB9 Polyclonal Antibody | anti-SERPINB9 antibody

Anti-SERPINB9 Antibody

Gene Names
SERPINB9; PI9; CAP3; PI-9; CAP-3
Reactivity
Human. Predicted: Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity purified
Synonyms
SERPINB9; Polyclonal Antibody; Anti-SERPINB9 Antibody; anti-SERPINB9 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human. Predicted: Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity purified
Form/Format
Liquid
Concentration
100ug/100ul (varies by lot)
Sequence Length
4121
Applicable Applications for anti-SERPINB9 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA titer: 1:20,000-1:80,000
Western blot analysis: 1:500-1:1,000
Optimal dilutions/concentrations should be determined by the end user
Storage Buffer
PBS, pH 7.4 with 0.02% Sodium Azide
Immunogen
Raised against a recombinate human SERPINB9 protein 66-328aa (BC002538)
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

Western Blot (WB)

Western Blot (WB)
Related Product Information for anti-SERPINB9 antibody
Rabbit Polyclonal Antibody
References
Rousalova,I., Krepela,E., Prochazka,J.,et al. Expression of proteinase inhibitor-9/serpinB9 in non-small cell lung carcinoma cells and tissues.Int. J. Oncol. 36 (1), 275-283 (2010)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
42,404 Da
NCBI Official Full Name
Homo sapiens serpin peptidase inhibitor, clade B (ovalbumin), member 9, mRNA
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade B (ovalbumin), member 9
NCBI Official Symbol
SERPINB9
NCBI Official Synonym Symbols
PI9; CAP3; PI-9; CAP-3
NCBI Protein Information
serpin B9; cytoplasmic antiproteinase 3; peptidase inhibitor 9; protease inhibitor 9 (ovalbumin type); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9; serpin peptidase inhibitor, clade B, member 9
UniProt Protein Name
Serpin B9
Protein Family
UniProt Gene Name
SERPINB9
UniProt Entry Name
SPB9_HUMAN

NCBI Description

This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq, Mar 2012]

Uniprot Description

SERPINB9: Granzyme B inhibitor. Belongs to the serpin family. Ov-serpin subfamily.

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: extracellular space; membrane; cytoplasm; intracellular; nucleus; cytosol

Molecular Function: serine-type endopeptidase inhibitor activity; protein binding; protease binding; caspase inhibitor activity

Biological Process: mast cell mediated immunity; response to bacterium; immune response; negative regulation of caspase activity; negative regulation by symbiont of host apoptosis; protection from natural killer cell mediated cytotoxicity; negative regulation of apoptosis

Research Articles on SERPINB9

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Product Notes

The SERPINB9 serpinb9 (Catalog #AAA416128) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SERPINB9 Antibody reacts with Human. Predicted: Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SERPINB9 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1:1,000 Optimal dilutions/concentrations should be determined by the end user. Researchers should empirically determine the suitability of the SERPINB9 serpinb9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SERPINB9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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