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Mouse Ricin Antibody

Anti-Ricin, RCA60 From Ricinus Communis Antibody

Applications
ELISA, Western Blot
Purity
Chromatography On Protein G Sepharose
Synonyms
Ricin; Anti-Ricin; RCA60 From Ricinus Communis Antibody; anti-Ricin antibody
Ordering
For Research Use Only!
Host
Mouse
Isotype
IgG1 for MAbs RA999
Clone Number
RA999
Specificity
MAbs RA999 recognize the A-chain of RCA60.The antibodies recognize also RCA120. The matched pair RA999 (coating) and RB999 (conjugate) has a detection limit for RCA60 of 100 pg/ml and shows no cross-reactivity for RCA120.
Purity/Purification
Chromatography On Protein G Sepharose
Form/Format
Liquid; PBS, pH 7.4 with 0.05% sodium azide.
Concentration
1ug/ul (varies by lot)
Sequence Length
565
Applicable Applications for anti-Ricin antibody
ELISA (EIA), Western Blot (WB)
Application Notes
MAbs are working in ELISA. All MAbs (except CP23) are working also in Western blotting.
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use.
For extended storage, aliquot contents and freeze at-20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Related Product Information for anti-Ricin antibody
This product is sold as an antibody preparation for research use only. Standard Laboratory Practices should be followed when handling this material. Contains sodium azide (0.1%) as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

NCBI and Uniprot Product Information

NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
ricin
UniProt Protein Name
Ricin
Protein Family
UniProt Entry Name
RICI_RICCO

Uniprot Description

Ricin is highly toxic to animal cells and to a lesser extent to plant cells. The A chain acts as a glycosidase that removes a specific adenine residue from an exposed loop of the 28S rRNA (A4324 in mammals), leading to rRNA breakage. As this loop is involved in elongation factor binding, modified ribosomes are catalytically inactive and unable to support protein synthesis. The A chain can inactivate a few thousand ribosomes per minute, faster than the cell can make new ones. Therefore a single A chain molecule can kill an animal cell. The B chain binds to beta-D-galactopyranoside moieties on cell surface glycoproteins and glycolipids and facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (Lectin activity).

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Product Notes

The Ricin (Catalog #AAA4158926) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Ricin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). MAbs are working in ELISA. All MAbs (except CP23) are working also in Western blotting. Researchers should empirically determine the suitability of the Ricin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ricin, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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