IHC (Immunohiostchemistry)
(Immunohistochemistry of TEM4 in human spleen tissue with TEM4 antibody at 2.5 μg/mL.)
Rabbit anti-Human TEM4 Polyclonal Antibody | anti-ARHGEF17 antibody
TEM4 Antibody
Gene Names
ARHGEF17; TEM4; P164RHOGEF; p164-RhoGEF
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
TEM4 Antibody is affinity chromatography purified via peptide column.
Synonyms
TEM4, Antibody; TEM4 Antibody; TEM4; P164RHOGEF; p164-RhoGEF; KIAA0337; Rho guanine nucleotide exchange factor 17; 164 kDa Rho-specific guanine-nucleotide exchange factor; Rho guanine nucleotide exchange factor (GEF) 17; anti-ARHGEF17 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
TEM4 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
2063
Applicable Applications for anti-ARHGEF17 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4.
Buffer
TEM4 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TEM4 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of TEM4 in human spleen tissue with TEM4 antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TEM4 in human spleen tissue with TEM4 antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of TEM4 in Jurkat cell lysate with TEM4 antibody at (A) 0.5 and (B) 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of TEM4 in Jurkat cell lysate with TEM4 antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-ARHGEF17 antibody
TEM4 Antibody: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
221,673 Da
NCBI Official Full Name
Rho guanine nucleotide exchange factor 17
NCBI Official Synonym Full Names
Rho guanine nucleotide exchange factor (GEF) 17
NCBI Official Symbol
ARHGEF17
NCBI Official Synonym Symbols
TEM4; P164RHOGEF; p164-RhoGEF
NCBI Protein Information
rho guanine nucleotide exchange factor 17; tumor endothelial marker 4; 164 kDa Rho-specific guanine-nucleotide exchange factor; Rho-specific guanine-nucleotide exchange factor 164 kDa
UniProt Protein Name
Rho guanine nucleotide exchange factor 17
UniProt Gene Name
ARHGEF17
UniProt Synonym Gene Names
KIAA0337; TEM4; p164-RhoGEF; p164RhoGEF
UniProt Entry Name
ARHGH_HUMAN
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Product Notes
The ARHGEF17 arhgef17 (Catalog #AAA39980) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TEM4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TEM4 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the ARHGEF17 arhgef17 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TEM4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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