SDS-Page
(Recombinant MLLT1 / ENL (1-148) protein gel 12.5% SDS-PAGE Coomassie staining MW: 21.9 kDa Purity: >85% )
MLLT1/ENL recombinant protein
Recombinant MLLT1/ENL (1-148) protein
Shipping Temp: Dry Ice
SDS-Page
(Recombinant MLLT1 / ENL (1-148) protein gel 12.5% SDS-PAGE Coomassie staining MW: 21.9 kDa Purity: >85% )
SDS-Page
(Recombinant MLLT1 / ENL (1-148) protein gel 12.5% SDS-PAGE Coomassie staining MW: 21.9 kDa Purity: >85% )
Testing Data
(HTRF assay for MLLT1 / ENL (1-148) activity 3 ?M H3K27cr (crotonylated K27) peptide was incubated with different concentrations of MLLT1 / ENL (1-148) protein in a 10 ?l reaction system containing 50mM HEPES-NaOH pH7.5, 0.1% BSA for 1 hr, then 10 ?l DYKDDDDK antibody and SA-XL665 mixture (each 1:100 dilution in Reaction Buffer) was added to each reaction system and incubated for 30 min. All the operations and reactions were performed at RT. HTRF was used for detection.)
Testing Data
(HTRF assay for MLLT1 / ENL (1-148) activity 3 ?M H3K27cr (crotonylated K27) peptide was incubated with different concentrations of MLLT1 / ENL (1-148) protein in a 10 ?l reaction system containing 50mM HEPES-NaOH pH7.5, 0.1% BSA for 1 hr, then 10 ?l DYKDDDDK antibody and SA-XL665 mixture (each 1:100 dilution in Reaction Buffer) was added to each reaction system and incubated for 30 min. All the operations and reactions were performed at RT. HTRF was used for detection.)
Testing Data
(HTRF assay for MLLT1 / ENL (1-148) activity 3 ?M H3K27cr (crotonylated K27) peptide was incubated with different concentrations of MLLT1 / ENL (1-148) protein in a 10 ?l reaction system containing 50mM HEPES-NaOH pH7.5, 0.1% BSA for 1 hr, then 10 ?l DYKDDDDK antibody and SA-XL665 mixture (each 1:100 dilution in Reaction Buffer) was added to each reaction system and incubated for 30 min. All the operations and reactions were performed at RT. HTRF was used for detection.)
Testing Data
(HTRF assay for MLLT1 / ENL (1-148) activity 3 ?M H3K27cr (crotonylated K27) peptide was incubated with different concentrations of MLLT1 / ENL (1-148) protein in a 10 ?l reaction system containing 50mM HEPES-NaOH pH7.5, 0.1% BSA for 1 hr, then 10 ?l DYKDDDDK antibody and SA-XL665 mixture (each 1:100 dilution in Reaction Buffer) was added to each reaction system and incubated for 30 min. All the operations and reactions were performed at RT. HTRF was used for detection.)
Background: MLLT1/ENL (Myeloid/Lymphoid Or Mixed-Lineage Leukemia; Translocated To, 1), also known as YEATS1 or LTG19, is a component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.
NCBI and Uniprot Product Information
Uniprot Description
MLLT1: a transcriptional regulator that can activate transcription from synthetic reporter genes in both lymphoid and myeloid cells. A chromosomal aberration involving MLLT1 is associated with acute leukemias.
Protein type: Oncoprotein; Transcription regulation
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: nucleoplasm; transcription elongation factor complex; cytoplasm; nucleolus; nucleus
Molecular Function: protein binding; DNA binding
Biological Process: transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; negative regulation of protein kinase activity
Research Articles on MLLT1/ENL
Similar Products
Product Notes
The MLLT1/ENL mllt1 (Catalog #AAA389155) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MLLT1/ENL, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
