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Typical Testing Data/Standard Curve (for reference only)

Human Aldose Reductase ELISA Kit | AKR1B1 elisa kit

Human Aldose Reductase ELISA Kit

Gene Names
AKR1B1; AR; ADR; ALR2; ALDR1
Reactivity
Human
Synonyms
Aldose Reductase; Human Aldose Reductase ELISA Kit; AKR1B1 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
316
Samples
Serum, plasma, cell culture supernate and other biological fluids
Assay Type
Sandwich
Detection Range
62.5 pg/ml-1000 pg/ml
Sensitivity
1 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for AKR1B1 elisa kit
Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofALDOSE REDUCTASEin the sample, This ALDOSE REDUCTASEELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusALDOSE REDUCTASEconcentration. The concentration ofALDOSE REDUCTASEin the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
231
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
aldo-keto reductase family 1 member B1 isoform 1
NCBI Official Synonym Full Names
aldo-keto reductase family 1 member B
NCBI Official Symbol
AKR1B1
NCBI Official Synonym Symbols
AR; ADR; ALR2; ALDR1
NCBI Protein Information
aldo-keto reductase family 1 member B1
UniProt Protein Name
Aldose reductase
Protein Family
UniProt Gene Name
AKR1B1
UniProt Synonym Gene Names
ALDR1; AR
UniProt Entry Name
ALDR_HUMAN

NCBI Description

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009]

Uniprot Description

AKR1B1: Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. Belongs to the aldo/keto reductase family.

Protein type: Carbohydrate Metabolism - pentose and glucuronate interconversions; Oxidoreductase; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - galactose; EC 1.1.1.21; Lipid Metabolism - glycerolipid; Carbohydrate Metabolism - fructose and mannose

Chromosomal Location of Human Ortholog: 7q35

Cellular Component: nucleoplasm; extracellular space; cytoplasm; cytosol

Molecular Function: glyceraldehyde oxidoreductase activity; electron carrier activity; aldo-keto reductase activity; aldehyde reductase activity

Biological Process: steroid metabolic process; carbohydrate metabolic process; C21-steroid hormone biosynthetic process; response to stress

Research Articles on AKR1B1

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Product Notes

The Human AKR1B1 akr1b1 (Catalog #AAA3804831) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA3804831 ELISA Kit recognizes Human AKR1B1. It is sometimes possible for the material contained within the vial of "Aldose Reductase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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