Human Fatty Acyl-CoA Reductase 1 ELISA Kit | FAR1 elisa kit

Human Fatty Acyl-CoA Reductase 1 ELISA Kit

Cat. Num. AAA3804343

• Gene Names: FAR1; PFCRD; MLSTD2; SDR10E1
• Reactivity: Human
• Synonyms: Fatty Acyl-CoA Reductase 1; Human Fatty Acyl-CoA Reductase 1 ELISA Kit; FAR1 elisa kit

• Reactivity: Human
• Sequence Length: 1781

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 500 pg/ml-8000 pg/ml
• Sensitivity: 10 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for FAR1 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofFATTY ACYL-COA REDUCTASE 1in the sample, This FATTY ACYL-COA REDUCTASE 1ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusFATTY ACYL-COA REDUCTASE 1concentration. The concentration ofFATTY ACYL-COA REDUCTASE 1in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 33872399
• NCBI GeneID: 84188
• NCBI Official Full Name: Homo sapiens fatty acyl CoA reductase 1, mRNA
• NCBI Official Synonym Full Names: fatty acyl-CoA reductase 1
• NCBI Official Symbol: FAR1
• NCBI Official Synonym Symbols: PFCRD; MLSTD2; SDR10E1
• NCBI Protein Information: fatty acyl-CoA reductase 1
• Protein Family: Fatty acyl-CoA reductase

NCBI Description

The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015]