Human 40S Ribosomal Protein S3 ELISA Kit | RPS3 elisa kit

Human 40S Ribosomal Protein S3 ELISA Kit

Cat. Num. AAA3801983

• Reactivity: Human
• Synonyms: 40S Ribosomal Protein S3; Human 40S Ribosomal Protein S3 ELISA Kit; RPS3 elisa kit

• Reactivity: Human
• Sequence Length: 243

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 250 pg/ml-4000 pg/ml
• Sensitivity: 10 pg/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for RPS3 elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration of40S RIBOSOMAL PROTEIN S3in the sample, This 40S RIBOSOMAL PROTEIN S3ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versus40S RIBOSOMAL PROTEIN S3concentration. The concentration of40S RIBOSOMAL PROTEIN S3in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 924183575
• NCBI GeneID: 476804
• NCBI Accession #: NP_001300706.1
• NCBI GenBank Nucleotide #: NP_001300706.1
• UniProt Accession #: E2RH47
• NCBI Official Full Name: 40S ribosomal protein S3
• NCBI Official Synonym Full Names: ribosomal protein S3
• NCBI Official Symbol: RPS3
• NCBI Protein Information: 40S ribosomal protein S3
• UniProt Protein Name: 40S ribosomal protein S3
• Protein Family: 40S ribosomal protein
• UniProt Gene Name: RPS3

Uniprot Description

Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein OGG1. Enhances the uracil excision activity of UNG1. Also stimulates the cleavage of the phosphodiester backbone by APEX1. When located in the mitochondrion, reduces cellular ROS levels and mitochondrial DNA damage. Has also been shown to negatively regulate DNA repair in cells exposed to hydrogen peroxide. Plays a role in regulating transcription as part of the NF-kappa-B p65-p50 complex where it binds to the RELA/p65 subunit, enhances binding of the complex to DNA and promotes transcription of target genes. Represses its own translation by binding to its cognate mRNA. Binds to and protects TP53/p53 from MDM2-mediated ubiquitination. Involved in spindle formation and chromosome movement during mitosis by regulating microtubule polymerization. Involved in induction of apoptosis through its role in activation of CASP8. Induces neuronal apoptosis by interacting with the E2F1 transcription factor and acting synergistically with it to up-regulate pro-apoptotic proteins BCL2L11/BIM and HRK/Dp5. Interacts with TRADD following exposure to UV radiation and induces apoptosis by caspase-dependent JNK activation.