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ICC (Immunocytochemistry)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CLNS1A mAb. [Lot No. 2187C2a-1])
Mouse anti-Human CLNS1A Monoclonal Antibody | anti-CLNS1A antibody
Mouse monoclonal antibody Anti-Human CLNS1A
Gene Names
CLNS1A; CLCI; ICln; CLNS1B
Reactivity
Human
Applications
Western Blot, Immunocytochemistry, Dot Blot
Synonyms
CLNS1A, Antibody; Mouse monoclonal antibody Anti-Human CLNS1A; Homo sapiens chloride channel, nucleotide-sensitive, 1A (CLNS1A); CLCI; ICln; CLNS1B; anti-CLNS1A antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2187C2a
Concentration
100 ug/ml (1.0 ml) (varies by lot)
Sequence Length
1378
Applicable Applications for anti-CLNS1A antibody
WB (Western Blot), ICC (Immunocytochemistry), DB (Dot Blot)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
ICC (Immunocytochemistry)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CLNS1A mAb. [Lot No. 2187C2a-1])
ICC (Immunocytochemistry)
(Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-CLNS1A mAb. [Lot No. 2187C2a-1])
WB (Western Blot)
(Detection of CLNS1A by Western blot.Samples: Whole cell lysate from human HEK293 (H, 25 ug), mouse NIH3T3 (M, 25 ug) and rat F2408 (R, 25 ug) cells. [Lot No. 2187C2a-1]Predicted molecular weight: 26 kDa)
WB (Western Blot)
(Detection of CLNS1A by Western blot.Samples: Whole cell lysate from human HEK293 (H, 25 ug), mouse NIH3T3 (M, 25 ug) and rat F2408 (R, 25 ug) cells. [Lot No. 2187C2a-1]Predicted molecular weight: 26 kDa)
Quality Control #2
(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Quality Control #2
(Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Quality Control
(Western blot analysis of immunized recombinant protein, using anti-CLNS1A monoclonal antibody.)
Quality Control
(Western blot analysis of immunized recombinant protein, using anti-CLNS1A monoclonal antibody.)
Related Product Information for anti-CLNS1A antibody
The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway. [UniProtKB Function]
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
26,215 Da
NCBI Official Full Name
Homo sapiens chloride channel, nucleotide-sensitive, 1A (CLNS1A), mRNA
NCBI Official Synonym Full Names
chloride channel, nucleotide-sensitive, 1A
NCBI Official Symbol
CLNS1A
NCBI Official Synonym Symbols
CLCI; ICln; CLNS1B
NCBI Protein Information
methylosome subunit pICln; chloride channel regulatory protein; chloride channel, nucleotide sensitive 1A; chloride conductance regulatory protein ICln; chloride ion current inducer protein; i(Cln); reticulocyte pICln; reticulocyte protein ICln
UniProt Protein Name
Methylosome subunit pICln
UniProt Gene Name
CLNS1A
UniProt Entry Name
ICLN_HUMAN
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Product Notes
The CLNS1A clns1a (Catalog #AAA36432) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human CLNS1A reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's CLNS1A can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ICC (Immunocytochemistry), DB (Dot Blot). Researchers should empirically determine the suitability of the CLNS1A clns1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CLNS1A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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