Structure
Leonurine Biochemical
Leonurine
Purity
>98% (HPLC)
Synonyms
Leonurine; SCM-198; Leonurine biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 6mg/mL (19.27mM)
Target
Apaf-1
Receptor
Apaf-1
Chemical Name
Benzoic acid, 4-hydroxy-3, 5-dimethoxy-, ester with(4-hydroxybutyl)guanidine(8CI)
SMILES
O=C(OCCCCNC(N)=N)C1=CC(OC)=C(O)C(OC)=C1
Molecular Formula
C14H21N3O5
CAS Number
24697-74-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Leonurine biochemical
Leonurine (SCM-198) is a natural alkaloid that exhibits cardio-and neuronal-protective effects both in vitro and in vivo, occupies the caspase recruitment site of Apaf-1, blocks its interaction with procaspase-9; attenuates doxorubicin-induced apoptosis in H9c2 cardiac muscle cells, protects middle cerebral artery occluded rats through antioxidant effect and regulation of mitochondrial function, attenuates myocardial fibrotic response via inhibition of NADPH oxidase 4 (Nox4).
Product Categories/Family for Leonurine biochemical
References
1. Loh KP, et al. Stroke. 2010 Nov; 41 (11):2661-8.
2. Xin H, et al. Eur J Pharmacol. 2009 Jun 10; 612 (1-3):75-9.
3. Liu XH, et al. Free Radic Biol Med. 2013 Jan; 54:93-104.
4. Wang Y, et al. Sci Rep. 2016 Jul 22; 6:29820.
2. Xin H, et al. Eur J Pharmacol. 2009 Jun 10; 612 (1-3):75-9.
3. Liu XH, et al. Free Radic Biol Med. 2013 Jan; 54:93-104.
4. Wang Y, et al. Sci Rep. 2016 Jul 22; 6:29820.
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Product Notes
The Leonurine (Catalog #AAA3603718) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Leonurine, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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