Structure
Bromocriptine mesylate, Inhibitor
Bromocriptine mesylate
Purity
>98% (HPLC)
Synonyms
Bromocriptine mesylate; CB-154; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=30mg/mL
Target
Dopamine Receptor
Receptor
Dopamine Receptor
Chemical Name
Ergotaman-3', 6', 18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5alpha)-, methanesulfonate(1:1)
SMILES
O=C([C@H](C=C12)CN(C)[C@]2([H])CC3=C(Br)NC4=C3C1=CC=C4)N[C@@](O5)(C(C)C)C(N6[C@]5(O)[C@@](CCC7)([H])N7C([C@@H]6CC(C)C)=O)=O.CS(=O)(O)=O
Molecular Formula
C33H44BrN5O8S
CAS Number
22260-51-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Bromocriptine mesylate, inhibitor
Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter; decreases body fat in animal and human models and increases lean muscle mass, improves glucose intolerance and insulin resistance, and reduces triglycerides and free fatty acids; also induces apoptosis and decreases colony formation in AML cells, shows synergy with standard agents and selectivity for the leukemic cell; reduces hyperphagia and adiposity in rats with diet-induced obesity. Diabetes Approved
Product Categories/Family for Bromocriptine mesylate, inhibitor
References
1. Shirasaki Y, et al. Eur J Pharmacol. 2010 Sep 15; 643 (1):48-57.
2. Oda T, et al. Eur J Pharmacol. 2008 Nov 19; 598 (1-3):27-31.
3. Wacker J, et al. Psychophysiology. 2006 Jul; 43 (4):372-81.
4. Liberante FG, et al. Oncotarget. 2016 Feb 9; 7 (6):6609-19.
2. Oda T, et al. Eur J Pharmacol. 2008 Nov 19; 598 (1-3):27-31.
3. Wacker J, et al. Psychophysiology. 2006 Jul; 43 (4):372-81.
4. Liberante FG, et al. Oncotarget. 2016 Feb 9; 7 (6):6609-19.
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Product Notes
The Bromocriptine mesylate (Catalog #AAA3603555) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Bromocriptine mesylate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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