Procalcitonin Recombinant Protein | PCT recombinant protein
Procalcitonin, PCT
Applications
ELISA, SDS-Page
Purity
>95% by SDS-PAGE
Synonyms
Procalcitonin; PCT; PCT recombinant protein
Host
E. Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Lyophilized from 0.01 M PBS (pH7.4) with 2% BSA and 0.03% Proclin 300.
Applicable Applications for PCT recombinant protein
ELISA (EIA), SDS-PAGE
Other applications have not been tested. The optimal dilutions should be determined by end user.
Other applications have not been tested. The optimal dilutions should be determined by end user.
Preparation and Storage
Shipping: Blue ice.
Upon receipt, aliquot and store at -20°C or -80°C for long term.
Avoid repeated freeze and thaw cycles
Upon receipt, aliquot and store at -20°C or -80°C for long term.
Avoid repeated freeze and thaw cycles
Related Product Information for PCT recombinant protein
Recombinant human PCT protein with 6×His tag at N-terminal
Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It iscomposed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. The level of procalcitonin in the blood stream of healthy individuals is below the limit of detection (10 pg/mL) of clinical assays. Itslevel rises in a response to a proinflammatory stimulus, especially of bacterial origin. Measurement of PCT concentrations during multiple organ dysfunction syndrome provides more information about the severity and the course of the disease than that of CRP. It can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha.
Procalcitonin (PCT) is a peptide precursor of the hormone calcitonin, the latter being involved with calcium homeostasis. It iscomposed of 116 amino acids and is produced by parafollicular cells (C cells) of the thyroid and by the neuroendocrine cells of the lung and the intestine. The level of procalcitonin in the blood stream of healthy individuals is below the limit of detection (10 pg/mL) of clinical assays. Itslevel rises in a response to a proinflammatory stimulus, especially of bacterial origin. Measurement of PCT concentrations during multiple organ dysfunction syndrome provides more information about the severity and the course of the disease than that of CRP. It can be used as a marker of severe sepsis caused by bacteria and generally grades well with the degree of sepsis, although levels of procalcitonin in the blood are very low. PCT has the greatest sensitivity (85%) and specificity (91%) for differentiating patients with systemic inflammatory response syndrome (SIRS) from those with sepsis, when compared with IL-2, IL-6, IL-8, CRP and TNF-alpha.
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Product Notes
The PCT (Catalog #AAA355754) is a Recombinant Protein produced from E. Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Procalcitonin can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), SDS-PAGE Other applications have not been tested. The optimal dilutions should be determined by end user. Researchers should empirically determine the suitability of the PCT for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Procalcitonin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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