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Immunohistochemistry (IHC) (Napsin A on Kidney)

Mouse anti-Human Napsin A Monoclonal Antibody | anti-NAPSA antibody

Napsin A

Gene Names
NAPSA; KAP; Kdap; NAP1; NAPA; SNAPA
Reactivity
Human
Applications
Dilution Range: 1:50-1:200
Synonyms
Napsin A; Monoclonal Antibody; anti-NAPSA antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Sequence Length
420
Applicable Applications for anti-NAPSA antibody
Dilution Range: 1:50-1:200
Positive Control
Lung Adenocarcinoma, Kidney, Renal Cell Carcinoma

Immunohistochemistry (IHC)

(Napsin A on Kidney)

Immunohistochemistry (IHC) (Napsin A on Kidney)
Related Product Information for anti-NAPSA antibody
Napsin A is a pepsin-like aspartic proteinase, closely related to Napsin B, expressed mainly in the lung and kidney and which is involved in the correct folding, targeting, and control of aspartic proteinase zymogens. Napsin A expression has been indicated in type II pneumocytes and adenocarcinomas of the lung and kidney. Anti-Napsin A is also useful for differentiating between primary lung adenocarcinomas and adenocarcinomas of other organs, due to the high specificity expression of Napsin A in adenocarcinomas of the lung.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
napsin-A preproprotein
NCBI Official Synonym Full Names
napsin A aspartic peptidase
NCBI Official Symbol
NAPSA
NCBI Official Synonym Symbols
KAP; Kdap; NAP1; NAPA; SNAPA
NCBI Protein Information
napsin-A
UniProt Protein Name
Napsin-A
Protein Family
UniProt Gene Name
NAPSA
UniProt Synonym Gene Names
NAP1; NAPA; ASP4; Asp 4
UniProt Entry Name
NAPSA_HUMAN

NCBI Description

This gene encodes a member of the peptidase A1 family of aspartic proteases. The encoded preproprotein is proteolytically processed to generate an activation peptide and the mature protease. The activation peptides of aspartic proteinases function as inhibitors of the protease active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules. This gene has been described as a marker for lung adenocarcinoma and renal cell carcinoma. [provided by RefSeq, Feb 2016]

Uniprot Description

NAPSA: May be involved in processing of pneumocyte surfactant precursors. Belongs to the peptidase A1 family.

Protein type: EC 3.4.23.-; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: extracellular space; lysosome

Molecular Function: aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity

Biological Process: cellular protein metabolic process; membrane protein proteolysis; protein catabolic process; surfactant homeostasis

Research Articles on NAPSA

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Product Notes

The NAPSA napsa (Catalog #AAA344126) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Napsin A reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Napsin A can be used in a range of immunoassay formats including, but not limited to, Dilution Range: 1:50-1:200. Researchers should empirically determine the suitability of the NAPSA napsa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Napsin A, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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