Hamster Thioredoxin Binding Protein 2 ELISA Kit | TBP2 elisa kit
Hamster Thioredoxin Binding Protein 2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
TXNIP: May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over- expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Belongs to the arrestin family.
Protein type: Motility/polarity/chemotaxis; Tumor suppressor; Mitochondrial; Apoptosis
Chromosomal Location of Human Ortholog: 1q21.1
Cellular Component: cytoplasm; mitochondrial intermembrane space; cytosol; nucleus
Molecular Function: enzyme inhibitor activity; protein binding; ubiquitin protein ligase binding
Biological Process: response to drug; transcription, DNA-dependent; positive regulation of apoptosis; platelet-derived growth factor receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; negative regulation of cell division; cell cycle; response to estradiol stimulus; regulation of cell proliferation; keratinocyte differentiation; response to hydrogen peroxide; protein import into nucleus; response to mechanical stimulus; negative regulation of catalytic activity; response to glucose stimulus; innate immune response; response to calcium ion; response to progesterone stimulus
Research Articles on TBP2
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Product Notes
The Hamster TBP2 txnip (Catalog #AAA034351) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA034351 ELISA Kit recognizes Hamster TBP2. It is sometimes possible for the material contained within the vial of "Thioredoxin Binding Protein 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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